CAJ | 학술논문

目的：：评价超脉冲CO2激光联合5－氨基酮戊酸光动力( ALA－PDT)治疗结节囊肿性痤疮的疗效及安全性。方法：68例IV级痤疮患者随机分为2组，每组34例，分别用超脉冲CO2激光联合ALA－PDT(治疗组)及单纯ALA－PDT治疗(对照组)，每周治疗1次，共3次。结果：治疗组痊愈率和有效率分别为70.5％和85.3％高于对照组的44.1％和61.8％(均P<0.05)；随访6个月，治疗组的复发率为5.9％低于对照组的23.5％，差异有统计学意义( P<0.05)。结论：超脉冲CO2激光联合ALA－PDT较单纯ALA－PDT治疗结节囊肿性痤疮疗效好，复发率低。
목적：：평개초맥충CO2격광연합5－안기동무산광동력( ALA－PDT)치료결절낭종성좌창적료효급안전성。방법：68례IV급좌창환자수궤분위2조，매조34례，분별용초맥충CO2격광연합ALA－PDT(치료조)급단순ALA－PDT치료(대조조)，매주치료1차，공3차。결과：치료조전유솔화유효솔분별위70.5％화85.3％고우대조조적44.1％화61.8％(균P<0.05)；수방6개월，치료조적복발솔위5.9％저우대조조적23.5％，차이유통계학의의( P<0.05)。결론：초맥충CO2격광연합ALA－PDT교단순ALA－PDT치료결절낭종성좌창료효호，복발솔저。
Objective:To assess the efficacy and safety of combination of ultrapulse carbon dioxide laser and ALA-PDT in the treatment of nodular and cystic acne. Methods:Sixty-eight patients with IV acne were randomly divided into the treatment group and the control group, 34 patients in each group. The patients in the treatment group were treated with ultrapulse carbon dioxide laser combined with ALA-PDT and those in the control group were treated with ALA-PDT group only, once every week for 3 times. Results: The cure rate and effective rate were 70.5% and 85.3% in the treatment group, which was higher than those in the control group (44.1% and 61.8%), with significant differences (P<0.05). Conclusion: Ultrapulse carbon dioxide laser combined with ALA-PDT is more effective than ALP-PDT alone in the treatment of nodular and cystic acne.