CAJ | 학술논문

淋巴瘤样丘疹病是一种低度恶性的T细胞淋巴瘤,属于皮肤CD30阳性淋巴增生性疾病谱中的一种疾病.临床表现为坏死性丘疹或结节,消退后可遗留浅表瘢痕,皮损具有复发性和自愈性,通常可见不同时期的皮损共存.组织学表现多样,呈现出谱系改变,主要特点是出现CD30阳性的肿瘤细胞,易和其他良恶性疾病相混淆.淋巴瘤样丘疹病尚无特效的治疗方法,现有治疗均不能改变疾病的自然病程,一般不需要积极治疗.本病预后良好,但有继发其他恶性淋巴瘤的可能,需要长期随访.
림파류양구진병시일충저도악성적T세포림파류,속우피부CD30양성림파증생성질병보중적일충질병.림상표현위배사성구진혹결절,소퇴후가유류천표반흔,피손구유복발성화자유성,통상가견불동시기적피손공존.조직학표현다양,정현출보계개변,주요특점시출현CD30양성적종류세포,역화기타량악성질병상혼효.림파류양구진병상무특효적치료방법,현유치료균불능개변질병적자연병정,일반불수요적겁치료.본병예후량호,단유계발기타악성림파류적가능,수요장기수방.
Lymphomatoid papulosis (LyP),a low-grade malignant T-cell lymphoma,belongs to the spectrum of cutaneous CD30 + lymphoproliferative diseases.It clinically manifests as necrotic papules or nodules,and superficial scar may be left after regression in some cases.Since lesions tend to recur and heal spontaneously,the lesions at different stages of evolution usually coexist.The histologic manifestations of LyP are various,and usually present as a spectrum.Pathologically,LyP is characterized by the presence of CD30+ neoplastic cells,and can easily be mistaken for other benign or malignant diseases.At present,no specific treatments for LyP are available,and no treatments can alter the natural history of LyP.In general,active treatments are not recommended.LyP has a good prognosis,but may be followed by other malignant lymphomas,so a long-term follow-up is warranted.