中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
42期
6808-6812
,共5页
组织构建%组织工程%绝经后%围绝经期%绝经前%静息能量消耗%体成分%全身脂肪含量%骨密度
組織構建%組織工程%絕經後%圍絕經期%絕經前%靜息能量消耗%體成分%全身脂肪含量%骨密度
조직구건%조직공정%절경후%위절경기%절경전%정식능량소모%체성분%전신지방함량%골밀도
背景：女性绝经后雌激素水平下降、年龄增长、活动水平下降都可能引起静息能量消耗的降低，进而引起绝经后女性体成分变化，导致疾病，如肥胖、骨折。目的：观察绝经前、围绝经期、绝经后妇女体成分及静息代谢率的变化。方法：收集门诊就诊的2312例妇女，其中绝经前1310例、围绝经期790例、绝经后212例，测定体成分和静息能量消耗。结果与结论：①围绝经期和绝经后女性的全身脂肪百分比显著高于绝经前女性。②3组间的静息代谢率无显著差异，经体质量校正后围绝经期女性的每千克体质量静息代谢率显著低于绝经前女性。③绝经后女性的骨密度、股骨颈抗骨折能力、下肢最大肌力、下肢肌肉分布系数显著低于围绝经期女性和绝经前女性(P<0.05)。④体质量、下肢肌肉分布系数与每千克体质量静息代谢率呈正相关，身高、体质量指数、全身脂肪含量与每千克体质量静息代谢率呈负相关。以上结果表明，绝经后女性体成分发生变化，身体脂肪含量增加，肌肉含量减少，骨量减少；骨骼、肌肉、关节功能处于退行性变；体成分改变与静息能量消耗之间存在一定的相互关系。
揹景：女性絕經後雌激素水平下降、年齡增長、活動水平下降都可能引起靜息能量消耗的降低，進而引起絕經後女性體成分變化，導緻疾病，如肥胖、骨摺。目的：觀察絕經前、圍絕經期、絕經後婦女體成分及靜息代謝率的變化。方法：收集門診就診的2312例婦女，其中絕經前1310例、圍絕經期790例、絕經後212例，測定體成分和靜息能量消耗。結果與結論：①圍絕經期和絕經後女性的全身脂肪百分比顯著高于絕經前女性。②3組間的靜息代謝率無顯著差異，經體質量校正後圍絕經期女性的每韆剋體質量靜息代謝率顯著低于絕經前女性。③絕經後女性的骨密度、股骨頸抗骨摺能力、下肢最大肌力、下肢肌肉分佈繫數顯著低于圍絕經期女性和絕經前女性(P<0.05)。④體質量、下肢肌肉分佈繫數與每韆剋體質量靜息代謝率呈正相關，身高、體質量指數、全身脂肪含量與每韆剋體質量靜息代謝率呈負相關。以上結果錶明，絕經後女性體成分髮生變化，身體脂肪含量增加，肌肉含量減少，骨量減少；骨骼、肌肉、關節功能處于退行性變；體成分改變與靜息能量消耗之間存在一定的相互關繫。
배경：녀성절경후자격소수평하강、년령증장、활동수평하강도가능인기정식능량소모적강저，진이인기절경후녀성체성분변화，도치질병，여비반、골절。목적：관찰절경전、위절경기、절경후부녀체성분급정식대사솔적변화。방법：수집문진취진적2312례부녀，기중절경전1310례、위절경기790례、절경후212례，측정체성분화정식능량소모。결과여결론：①위절경기화절경후녀성적전신지방백분비현저고우절경전녀성。②3조간적정식대사솔무현저차이，경체질량교정후위절경기녀성적매천극체질량정식대사솔현저저우절경전녀성。③절경후녀성적골밀도、고골경항골절능력、하지최대기력、하지기육분포계수현저저우위절경기녀성화절경전녀성(P<0.05)。④체질량、하지기육분포계수여매천극체질량정식대사솔정정상관，신고、체질량지수、전신지방함량여매천극체질량정식대사솔정부상관。이상결과표명，절경후녀성체성분발생변화，신체지방함량증가，기육함량감소，골량감소；골격、기육、관절공능처우퇴행성변；체성분개변여정식능량소모지간존재일정적상호관계。
BACKGROUND:Aging, lack of estrogen and few activities may lead to the decrease of resting energy expenditure in menopause women so as to induce the body composition changes, which can result in disease, such as obesity and fracture. OBJECTIVE:To explore the change of body composition and resting metabolic rate among premenopausal, perimenopausal and postmenopausal women. METHODS:2 312 women who came to outpatient clinic were recruited, including 1 310 premenopausal women, 790 perimenopausal women and 212 postmenopausal women. Body composition and resting energy expenditure were measured in each woman. RESULTS AND CONCLUSION:(1) Body fat percentage of perimenopausal and postmenopausal women was significantly higher than that of pre-menopausal women. (2) There was no significant difference in resting metabolic rate among the three groups. When adjusted body weight, the resting energy expenditure per kilogram was significantly lower in perimenopausal women than in premenopausal women. (3) Bone mineral density, femoral neck strength, lower limb maximal strength, and leg muscle distribution coefficient were significantly lower in postmenopausal women than in perimenopausal and premenopausal women (P < 0.05). (4) Weight and leg muscle distribution coefficient were positively correlated with the resting energy expenditure per kilogram, and height, body mass index, body fat percentage were negatively correlated with the resting energy expenditure per kilogram. These findings indicate that the body composition can change in women after menopause, such as body fat increasing, muscle content decreasing, and bone mass loss. There is a certain relationship between the change in body composition and resting energy expenditure.
