中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
43期
6958-6961
,共4页
杨永辉%孙厚杰%王少飞%晁建虎%雷小平
楊永輝%孫厚傑%王少飛%晁建虎%雷小平
양영휘%손후걸%왕소비%조건호%뢰소평
生物材料%骨生物材料%骨水泥%经皮椎体成形%椎体骨质疏松性压缩性骨折%并发症%疗效
生物材料%骨生物材料%骨水泥%經皮椎體成形%椎體骨質疏鬆性壓縮性骨摺%併髮癥%療效
생물재료%골생물재료%골수니%경피추체성형%추체골질소송성압축성골절%병발증%료효
背景:经皮穿刺椎体成形骨水泥注射治疗具有微创、时间短、可有效恢复椎体高度、防止椎体进一步塌陷、止痛效果明显等优点,成为治疗老年骨质疏松性压缩骨折的有效方法。目的:观察老年骨质疏松性压缩骨折经皮椎体成形骨水泥注射的治疗效果。方法:纳入62例骨质疏松性胸腰椎压缩骨折患者,其中男22例,女40例,年龄55-92岁,累及86椎体,均在C形臂X射线机透视下行经皮椎体成形聚甲基丙烯酸甲酯骨水泥注射治疗。治疗后随访12-36个月,对比治疗前后的目测类比评分、Cobb角与Oswestry功能障碍指数评分。结果与结论:治疗后随访12-36个月,11例出现并发症,其中骨水泥渗漏7例,临近椎体骨折2例,骨水泥拖尾1例,疼痛缓解不理想1例;末次随访的Cobb角、目测类比评分、Oswestry功能障碍指数评分均较治疗前显著改善(P <0.05)。表明椎体成形聚甲基丙烯酸甲酯骨水泥注射治疗老年骨质疏松性压缩骨折,不仅能恢复伤椎外形、减少后凸畸形、重建脊柱稳定性,而且能明显减轻骨折所致疼痛,改善患者生活质量,短中期疗效肯定。
揹景:經皮穿刺椎體成形骨水泥註射治療具有微創、時間短、可有效恢複椎體高度、防止椎體進一步塌陷、止痛效果明顯等優點,成為治療老年骨質疏鬆性壓縮骨摺的有效方法。目的:觀察老年骨質疏鬆性壓縮骨摺經皮椎體成形骨水泥註射的治療效果。方法:納入62例骨質疏鬆性胸腰椎壓縮骨摺患者,其中男22例,女40例,年齡55-92歲,纍及86椎體,均在C形臂X射線機透視下行經皮椎體成形聚甲基丙烯痠甲酯骨水泥註射治療。治療後隨訪12-36箇月,對比治療前後的目測類比評分、Cobb角與Oswestry功能障礙指數評分。結果與結論:治療後隨訪12-36箇月,11例齣現併髮癥,其中骨水泥滲漏7例,臨近椎體骨摺2例,骨水泥拖尾1例,疼痛緩解不理想1例;末次隨訪的Cobb角、目測類比評分、Oswestry功能障礙指數評分均較治療前顯著改善(P <0.05)。錶明椎體成形聚甲基丙烯痠甲酯骨水泥註射治療老年骨質疏鬆性壓縮骨摺,不僅能恢複傷椎外形、減少後凸畸形、重建脊柱穩定性,而且能明顯減輕骨摺所緻疼痛,改善患者生活質量,短中期療效肯定。
배경:경피천자추체성형골수니주사치료구유미창、시간단、가유효회복추체고도、방지추체진일보탑함、지통효과명현등우점,성위치료노년골질소송성압축골절적유효방법。목적:관찰노년골질소송성압축골절경피추체성형골수니주사적치료효과。방법:납입62례골질소송성흉요추압축골절환자,기중남22례,녀40례,년령55-92세,루급86추체,균재C형비X사선궤투시하행경피추체성형취갑기병희산갑지골수니주사치료。치료후수방12-36개월,대비치료전후적목측류비평분、Cobb각여Oswestry공능장애지수평분。결과여결론:치료후수방12-36개월,11례출현병발증,기중골수니삼루7례,림근추체골절2례,골수니타미1례,동통완해불이상1례;말차수방적Cobb각、목측류비평분、Oswestry공능장애지수평분균교치료전현저개선(P <0.05)。표명추체성형취갑기병희산갑지골수니주사치료노년골질소송성압축골절,불부능회복상추외형、감소후철기형、중건척주은정성,이차능명현감경골절소치동통,개선환자생활질량,단중기료효긍정。
BACKGROUND:Percutaneous vertebroplasty with bone cement injection has the advantages of minimal invasion, short time, effectively restoring vertebral body height, preventing further colapse of the vertebral body and obvious analgesic effect, which has became an effective method for the treatment of elderly osteoporotic compression fractures. OBJECTIVE:To observe the therapeutic effect of percutaneous vertebroplasty with bone cement injection on elderly osteoporotic compression fractures. METHODS:Sixty-two patients with osteoporotic thoracolumbar vertebral compression fracture, including 22 males and 40 females, aged 55-92 years, involving 86 vertebrae, were included and subjected to percutaneous vertebroplasty with polymethyl methacrylate bone cement injection under C-arm X-ray fluoroscopy. During the postoperative folow-up of 12 to 36 months, visual analogue scale scores, Cobb angle and Oswestry disability index scores were compared before and after the treatment. RESULTS AND CONCLUSION: At 12 to 36 months after treatment, there were 11 cases of complications, including 7 cases of bone cement leakage, 2 cases of adjacent vertebral fractures, 1 cases of bone cement tailing and 1 case of unsatisfactory pain relief. In the final folow-up, Cobb angle, visual analogue scale scores, Oswestry disability index scores were significantly improved compared with those before treatment (P < 0.05).These results demonstrate that percutaneous vertebroplasty with polymethyl methacrylate bone cement injection in the treatment of elderly osteoporotic compression fractures can not only restore vertebral shape, reduce kyphosis, reconstruct spinal stability, but also significantly reduce the pain caused by fractures and improve the life quality of patients. The curative effects in short and medium term are positive.