医学与社会
醫學與社會
의학여사회
Medicine and Society
2015年
11期
71-73,80
,共4页
贾海清%龙再秋%王晓彬%李联崑
賈海清%龍再鞦%王曉彬%李聯崑
가해청%룡재추%왕효빈%리련곤
人乳头瘤状病毒%宫颈上皮内瘤病变%筛查
人乳頭瘤狀病毒%宮頸上皮內瘤病變%篩查
인유두류상병독%궁경상피내류병변%사사
Human Papilla Virus%Cervical Intraepithelial Neoplasisa%Screening
目的:调查沈阳市某收容所女性高危型HPV( Human papillomavirus )感染率和宫颈上皮内瘤病变( Cervical intraep-ithelial neoplasisa , CIN)的现患率,及HPV感染的高危因素分析。方法:对沈阳市某收容所309名曾在娱乐场所工作的女性进行流行病学问卷调查,行TCT(Thin-Cytologic Test)及HPV检测,肉眼醋酸及碘实验,对HPV阳性或HPV阴性但TCT为ASCUS及以上者,进行阴道镜检查。结果:高危型HPV阳性率为46.9%,TCT阳性率为37.2%;宫颈CIN现患率为17.99%;高危型HPV感染率在各年龄组之间差异无统计学意义(P>0.05),50岁以上及20岁以下年龄组HPV感染率较高(85.71%,61.90%),31-40岁年龄组HPV感染率最低(41.07%)。HPV感染危险单因素分析,初次性生活年龄21-24岁OR值为0.40,95%CI为0.24-0.67,是HPV感染的保护因素;多因素分析,初次性生活年龄和绝经与HPV感染有关,初次性生活年龄OR值为0.699,95%CI为0.492-0.992,是HPV感染的保护因素;绝经OR值为2.93,95%CI为1.10-7.80,是HPV感染的危险因素。HPV感染与婚姻状况、性病史、吸烟、流产、口服避孕药、使用避孕套、定期体检、月经初潮年龄及从事性工作的时间无关。结论:沈阳市某收容所女性高危型HPV感染率和CIN的现患率均明显高于普通人群,说明该人群是HPV感染和患宫颈癌前病变的高危人群。
目的:調查瀋暘市某收容所女性高危型HPV( Human papillomavirus )感染率和宮頸上皮內瘤病變( Cervical intraep-ithelial neoplasisa , CIN)的現患率,及HPV感染的高危因素分析。方法:對瀋暘市某收容所309名曾在娛樂場所工作的女性進行流行病學問捲調查,行TCT(Thin-Cytologic Test)及HPV檢測,肉眼醋痠及碘實驗,對HPV暘性或HPV陰性但TCT為ASCUS及以上者,進行陰道鏡檢查。結果:高危型HPV暘性率為46.9%,TCT暘性率為37.2%;宮頸CIN現患率為17.99%;高危型HPV感染率在各年齡組之間差異無統計學意義(P>0.05),50歲以上及20歲以下年齡組HPV感染率較高(85.71%,61.90%),31-40歲年齡組HPV感染率最低(41.07%)。HPV感染危險單因素分析,初次性生活年齡21-24歲OR值為0.40,95%CI為0.24-0.67,是HPV感染的保護因素;多因素分析,初次性生活年齡和絕經與HPV感染有關,初次性生活年齡OR值為0.699,95%CI為0.492-0.992,是HPV感染的保護因素;絕經OR值為2.93,95%CI為1.10-7.80,是HPV感染的危險因素。HPV感染與婚姻狀況、性病史、吸煙、流產、口服避孕藥、使用避孕套、定期體檢、月經初潮年齡及從事性工作的時間無關。結論:瀋暘市某收容所女性高危型HPV感染率和CIN的現患率均明顯高于普通人群,說明該人群是HPV感染和患宮頸癌前病變的高危人群。
목적:조사침양시모수용소녀성고위형HPV( Human papillomavirus )감염솔화궁경상피내류병변( Cervical intraep-ithelial neoplasisa , CIN)적현환솔,급HPV감염적고위인소분석。방법:대침양시모수용소309명증재오악장소공작적녀성진행류행병학문권조사,행TCT(Thin-Cytologic Test)급HPV검측,육안작산급전실험,대HPV양성혹HPV음성단TCT위ASCUS급이상자,진행음도경검사。결과:고위형HPV양성솔위46.9%,TCT양성솔위37.2%;궁경CIN현환솔위17.99%;고위형HPV감염솔재각년령조지간차이무통계학의의(P>0.05),50세이상급20세이하년령조HPV감염솔교고(85.71%,61.90%),31-40세년령조HPV감염솔최저(41.07%)。HPV감염위험단인소분석,초차성생활년령21-24세OR치위0.40,95%CI위0.24-0.67,시HPV감염적보호인소;다인소분석,초차성생활년령화절경여HPV감염유관,초차성생활년령OR치위0.699,95%CI위0.492-0.992,시HPV감염적보호인소;절경OR치위2.93,95%CI위1.10-7.80,시HPV감염적위험인소。HPV감염여혼인상황、성병사、흡연、유산、구복피잉약、사용피잉투、정기체검、월경초조년령급종사성공작적시간무관。결론:침양시모수용소녀성고위형HPV감염솔화CIN적현환솔균명현고우보통인군,설명해인군시HPV감염화환궁경암전병변적고위인군。
Objective:To investigate the positive rate of high risk type HPV and incidence rates of CIN on women in penitentiary in Sheny-ang.Methods:309 female workers enrolled in this study, they received a personal standard risk factor interview and gynecological physical exam-ination including TCT and HPV sampling, and VIA examination, colostomy was conducted for those who were HPV-positive or HPV-negative but TCT≥ ASCUS, and biopsy would be provided later if any abnormal lesion existed.Results:High-risk HPV positive rate in the study group was 46.93%.The incidence rate of CIN was 17.99%.There were no significant differences among different age groups.HPV infection rate in two age groups (older than 50 and younger than 20) was higher and the value was 85.71%and 61.90%.Rate in the group of 31-40 year-old was the lowest and the value was 41.7%.Conclusion:The infection rates of High risk type HPV and incidence rates of CIN on these women are higher, which showed such population are in high risk for HPV infection and cervical intraepithelial neoplasisa.