CAJ | 학술논문

近视眼及圆锥角膜的发生、发展与巩膜及角膜的生物力学性能改变密切相关.准确测量角巩膜生物力学性能在眼部疾病的诊断、眼科手术技术的改进、眼部生物参数的测量和眼科医疗器械的研发等方面具有非常重要的意义.角巩膜组织构成眼球外壁,主要由致密交错的胶原纤维束和细胞外基质组成.角巩膜内部各层及各区域间胶原纤维的直径、间隙和数量分布的差异,使其生物力学特征颇为复杂,表现为非线弹性、黏弹性、各向异性、区域差异性和年龄相关性等.随着医疗检查诊断技术的发展,临床逐渐认识到眼部生物力学性能的重要性,但由于多数眼科医师对眼部生物力学性能的测量技术仍不甚了解,故笔者就国际上角巩膜生物力学性能测量技术的发展进行综述,为临床选取合适的测量平台与方法测量和研究角巩膜生物力学性能提供帮助.
근시안급원추각막적발생、발전여공막급각막적생물역학성능개변밀절상관.준학측량각공막생물역학성능재안부질병적진단、안과수술기술적개진、안부생물삼수적측량화안과의료기계적연발등방면구유비상중요적의의.각공막조직구성안구외벽,주요유치밀교착적효원섬유속화세포외기질조성.각공막내부각층급각구역간효원섬유적직경、간극화수량분포적차이,사기생물역학특정파위복잡,표현위비선탄성、점탄성、각향이성、구역차이성화년령상관성등.수착의료검사진단기술적발전,림상축점인식도안부생물역학성능적중요성,단유우다수안과의사대안부생물역학성능적측량기술잉불심료해,고필자취국제상각공막생물역학성능측량기술적발전진행종술,위림상선취합괄적측량평태여방법측량화연구각공막생물역학성능제공방조.
The occurrence and development of myopia and keratoconus is closely related to the changes of scleral and corneal biomechanical properties.The accurate measurement of biomechanical properties for corneoscleral fissure is very important on diagnosis of eye diseases, improvement of ocular operation, ocular biological parameter measurement and invention of ophthahnic instrument.Corneoscleral tissue, composed of bundles of compact and staggered collagen fiber and extracellular matrix, constitute the outer surface of the eyeball.The inhomogeneous distribution of the diameter, gap and amount of collagen fiber, makes its biomechanical characteristics really complex, characterized by nonlinear, viscoelastic, anisotropic, regional variation and age-related variation and etc.With the development of medical diagnostic technology, the importance of the ocular biomechanical property measurement is increasingly recognized.Nevertheless, measuring technology on ocular biomechanics properties are still not well understood by the majority of ophthalmologists.In order to facilitate the researchers to select a suitable measuring platform and method, the development of international corneoscleral biomechanical propertiy measuring technology was reviewed in this article.