CAJ | 학술논문

目的：观察参芪扶正注射液在胃癌术后辅助化疗中增加和稳定卡氏评分，减轻白细胞下降、恶心呕吐等毒副反应的疗效。方法：将70例胃癌术后患者随机分为治疗组、对照组各35例。治疗组采用参芪扶正注射液250 mL 静脉滴注，1次/d，连用12天，在化疗当天开始用药；对照组常规化疗。所有病例均治疗3个周期。结果：卡氏评分增加、稳定率治疗组为80%，对照组为42.85%，2组比较差异有统计学意义（P＜0.05）。白细胞下降、恶心呕吐、血小板减少、血红蛋白下降等毒副作用的发生率治疗组均低于对照组（P＜0.05）。结论：参芪扶正注射液能提高胃癌患者术后生活质量，减轻化疗引起的毒副作用。
목적：관찰삼기부정주사액재위암술후보조화료중증가화은정잡씨평분，감경백세포하강、악심구토등독부반응적료효。방법：장70례위암술후환자수궤분위치료조、대조조각35례。치료조채용삼기부정주사액250 mL 정맥적주，1차/d，련용12천，재화료당천개시용약；대조조상규화료。소유병례균치료3개주기。결과：잡씨평분증가、은정솔치료조위80%，대조조위42.85%，2조비교차이유통계학의의（P＜0.05）。백세포하강、악심구토、혈소판감소、혈홍단백하강등독부작용적발생솔치료조균저우대조조（P＜0.05）。결론：삼기부정주사액능제고위암환자술후생활질량，감경화료인기적독부작용。
Objective: To observe clinical effects of ShenQi FuZheng injection combined with chemotherapy in increasing and stabilizing Karnofsky (KPS) scores, relieving WBC decrease, toxicities such as nausea and vomiting in the adjunctive therapy for the patients after the surgery of gastric cancer. Methods: Seventy patients were randomized into the treatment group and the control group, 35 cases each group. The treatment group were given intravenous drip-ping of ShenQi FuZheng injection, 250mL, once per day, for 12 consecutive days, medicating at the day of chemother-apy given to the patients; the control group routine chemotherapy. Chemotherapy was performed for three cycles. Re-sults: KPS increase and stabilization rate of the treatment group was 80%, higher than 42.85% of the control group, the difference demonstrated statistical meaning (P<0.05). The treatment group was lower than the control group in the in-cidences of the toxicities including WBC decrease, nausea and vomiting, blood platelet decrease, hemoglobin decrease (P<0.05). Conclusion: ShenQi FuZheng injection could increase quality of life of the patients after the surgery of gas-tric cancer, and it could relieve the toxicity induced by chemotherapy.