西部中医药
西部中醫藥
서부중의약
Western Journal of Traditional Chinese Medicine
2015年
8期
111-112
,共2页
口腔溃疡,复发性%双黄连口服液%维生素 C%复发率
口腔潰瘍,複髮性%雙黃連口服液%維生素 C%複髮率
구강궤양,복발성%쌍황련구복액%유생소 C%복발솔
Shuanghuanglian oral%vitamin C%Erosive Oral Lichen Planus%adverse reactions%pain
目的：观察黄连口服液联合维生素 C 治疗复发性口腔溃疡( Recurrent oral ulceration，ROU)的临床疗效。方法：将60例患者随机分为观察组、对照组各30例，2组均采用西医常规治疗：曲安奈德注射液无菌棉签局部涂擦，5～10 mg/次，3次/d；维生素 C 片，50 mg/次，3次/d，口服。观察组同时口服双黄连口服液200 mL，3次/d。2组均连续治疗2周。结果：总有效率观察组为96.67%，对照组为83.33%，2组比较差异有统计学意义(P＜0.05)。 CD3+、CD4+、CD8+、CD4+/CD8+值2组治疗后均明显改善，观察组改善更明显(P＜0.05)。复发率观察组为6.67%，对照组为26.67%，2组比较差异有统计学意义(P＜0.05)。结论：双黄连口服液联合维生素 C 治疗 ROU 临床疗效显著，并可改善免疫功能，降低复发率。
目的：觀察黃連口服液聯閤維生素 C 治療複髮性口腔潰瘍( Recurrent oral ulceration，ROU)的臨床療效。方法：將60例患者隨機分為觀察組、對照組各30例，2組均採用西醫常規治療：麯安奈德註射液無菌棉籤跼部塗抆，5～10 mg/次，3次/d；維生素 C 片，50 mg/次，3次/d，口服。觀察組同時口服雙黃連口服液200 mL，3次/d。2組均連續治療2週。結果：總有效率觀察組為96.67%，對照組為83.33%，2組比較差異有統計學意義(P＜0.05)。 CD3+、CD4+、CD8+、CD4+/CD8+值2組治療後均明顯改善，觀察組改善更明顯(P＜0.05)。複髮率觀察組為6.67%，對照組為26.67%，2組比較差異有統計學意義(P＜0.05)。結論：雙黃連口服液聯閤維生素 C 治療 ROU 臨床療效顯著，併可改善免疫功能，降低複髮率。
목적：관찰황련구복액연합유생소 C 치료복발성구강궤양( Recurrent oral ulceration，ROU)적림상료효。방법：장60례환자수궤분위관찰조、대조조각30례，2조균채용서의상규치료：곡안내덕주사액무균면첨국부도찰，5～10 mg/차，3차/d；유생소 C 편，50 mg/차，3차/d，구복。관찰조동시구복쌍황련구복액200 mL，3차/d。2조균련속치료2주。결과：총유효솔관찰조위96.67%，대조조위83.33%，2조비교차이유통계학의의(P＜0.05)。 CD3+、CD4+、CD8+、CD4+/CD8+치2조치료후균명현개선，관찰조개선경명현(P＜0.05)。복발솔관찰조위6.67%，대조조위26.67%，2조비교차이유통계학의의(P＜0.05)。결론：쌍황련구복액연합유생소 C 치료 ROU 림상료효현저，병가개선면역공능，강저복발솔。
Objective: To investigate the effect of Shuanghuanglian oral combined vitamin C for treating Erosive Oral Lichen Planus. Methods: 60 Erosive Oral Lichen Planus patients were randomly equally divided accorded to the treatment group and the control group, the two groups were chosen injection of triamcinolone acetonide topical treat-ment, on the basis of the control group were given vitamin C treatment, and the treatment group were given Shuanghuanglian oral combined vitamin C treatment that were treated for 2 weeks. Results: After treatment, the re-sponse rates in the treatment group and the control group were 96.7% and 83.3% that the treatment group was signifi-cantly higher(P<0.05). After treatment, the pain scores were significantly lower than before treatment (P<0.05), while the pain scores in the treatment group after treatment were significantly lower than the control group (P<0.05). After treatment, after an investigation, the physiological function mental spiritual, social relations, treatment scores of the treatment group were significantly higher (P<0.05). The insomnia, rashes, headaches, infections during treatment in the treatment group were significantly less than the control treatment group (P<0.05). Conclusion: The Shuanghuan-glian oral combined vitamin C for treating Erosive Oral Lichen Planus can effectively relieve pain, improve the thera-peutic efficacy, its safety, and thus help to improve the quality of life outcomes.
