西部中医药
西部中醫藥
서부중의약
Western Journal of Traditional Chinese Medicine
2015年
8期
82-83,84
,共3页
胃炎,萎缩性,慢性%一贯煎%麦门冬汤
胃炎,萎縮性,慢性%一貫煎%麥門鼕湯
위염,위축성,만성%일관전%맥문동탕
chronic atrophic gastritis%YiGuanJian%MaiMenDong Tang
目的：观察一贯煎合麦门冬汤治疗慢性萎缩性胃炎（CAG）的临床疗效。方法：将84例 CAG 患者随机分为观察组、对照组各42例。对照组给予养阴清胃颗粒，冲服，15 g/d，2次/d。观察组给予一贯煎合麦门冬汤，每日1剂，水煎分服。2组均连续用药30天。结果：对照组临床治愈5例（11.90%），显效9例（21.43%），有效17例(40.48%)，无效11例(26.19%)，总有效率73.81%；观察组临床痊愈14例(33.33%)，显效20例(47.62%)，有效7例(16.67%)，无效1例(2.38%)，总有效率97.62%。观察组临床疗效优于对照组（P＜0.05）。血清 IL-8、IL-11和 TNF-α水平2组治疗后均明显改善（P＜0.05），观察组改善更明显（P＜0.05）。2组均无严重不良事件。结论：一贯煎合麦门冬汤治疗 CAG 临床疗效显著，可降低血清 IL-8、IL-11和 TNF-α水平，改善患者生活质量。
目的：觀察一貫煎閤麥門鼕湯治療慢性萎縮性胃炎（CAG）的臨床療效。方法：將84例 CAG 患者隨機分為觀察組、對照組各42例。對照組給予養陰清胃顆粒，遲服，15 g/d，2次/d。觀察組給予一貫煎閤麥門鼕湯，每日1劑，水煎分服。2組均連續用藥30天。結果：對照組臨床治愈5例（11.90%），顯效9例（21.43%），有效17例(40.48%)，無效11例(26.19%)，總有效率73.81%；觀察組臨床痊愈14例(33.33%)，顯效20例(47.62%)，有效7例(16.67%)，無效1例(2.38%)，總有效率97.62%。觀察組臨床療效優于對照組（P＜0.05）。血清 IL-8、IL-11和 TNF-α水平2組治療後均明顯改善（P＜0.05），觀察組改善更明顯（P＜0.05）。2組均無嚴重不良事件。結論：一貫煎閤麥門鼕湯治療 CAG 臨床療效顯著，可降低血清 IL-8、IL-11和 TNF-α水平，改善患者生活質量。
목적：관찰일관전합맥문동탕치료만성위축성위염（CAG）적림상료효。방법：장84례 CAG 환자수궤분위관찰조、대조조각42례。대조조급여양음청위과립，충복，15 g/d，2차/d。관찰조급여일관전합맥문동탕，매일1제，수전분복。2조균련속용약30천。결과：대조조림상치유5례（11.90%），현효9례（21.43%），유효17례(40.48%)，무효11례(26.19%)，총유효솔73.81%；관찰조림상전유14례(33.33%)，현효20례(47.62%)，유효7례(16.67%)，무효1례(2.38%)，총유효솔97.62%。관찰조림상료효우우대조조（P＜0.05）。혈청 IL-8、IL-11화 TNF-α수평2조치료후균명현개선（P＜0.05），관찰조개선경명현（P＜0.05）。2조균무엄중불량사건。결론：일관전합맥문동탕치료 CAG 림상료효현저，가강저혈청 IL-8、IL-11화 TNF-α수평，개선환자생활질량。
Objective: To observe clinical effects of YiGuanJian combined with MaiMenDong Tang in treating chronic atrophic gastritis (CAG). Methods: Eight-four CAG patients were randomized into the observation group and the control group, 42 cases each group. The control group took YangYinQingWei granules after mixing it with water, 15g/d, twice per day. The observation group were given YiGuanJian combined with MaiMenDong Tang, one dose each day, water decocted. Both groups were treated for 30 consecutive days. Results: There were five cases cured (11.90%), nine cases markedly effective (21.43%), 17 cases effective (40.48%), 11 cases ineffective (26.19%), total effective rate of the control group was 73.81%; there were 14 cases cured (33.33%), 20 cases markedly effective (47.62%), seven cases effective (16.67%), one cases ineffective (2.38%), total effective rate of the observation group was 97.62%. The observation group was superior to the control group in clinical effects (P<0.05). No adverse reaction occurred in both groups. Conclusion: YiGuanJian combined with MaiMenDong Tang are effective in treating CAG, the therapy could lower the levels of IL-8, IL-11 and TNF-α, as well as quality of life of the patients.
