中外女性健康研究
中外女性健康研究
중외녀성건강연구
Women's Health Research
2015年
20期
5-6
,共2页
乳腺癌%调强放射治疗%常规切线野治疗
乳腺癌%調彊放射治療%常規切線野治療
유선암%조강방사치료%상규절선야치료
Breast cancer%Intensity-modulated radiation therapy%Conventional tangential irradiation
目的：探究乳腺癌调强放射治疗和常规切线野治疗的三维剂量学差异。方法：选取2014年1月至2015年5月我院收治的7例乳腺癌患者，均行保乳手术后为其设计调强放射治疗和常规切线野治疗，并比较两种治疗方法在OARs与PTV上的三维剂量学差异。结果：两种放射治疗计划的靶区覆盖一致，95%靶体积接受50.0Gy的放疗剂量，99%的靶区体积接受95%的处方剂量；调强放射治疗与常规切线野治疗相比，V110%平均下降9.2%，差异具有统计学意义（P＜0.05）；3例左侧乳腺癌患者的心脏V30平均下降3.6%，差异具有统计学意义（P＜0.05）；同侧肺V20平均下降8.9%，同侧肺V30平均下降11.6%，组间差异均具有统计学意义（P＜0.05）。结论：调强放射治疗可以在保证靶区覆盖率的基础上，解决靶区剂量分布不均匀的问题，减少危及器官尤其是心脏、同侧肺的照射剂量和体积。
目的：探究乳腺癌調彊放射治療和常規切線野治療的三維劑量學差異。方法：選取2014年1月至2015年5月我院收治的7例乳腺癌患者，均行保乳手術後為其設計調彊放射治療和常規切線野治療，併比較兩種治療方法在OARs與PTV上的三維劑量學差異。結果：兩種放射治療計劃的靶區覆蓋一緻，95%靶體積接受50.0Gy的放療劑量，99%的靶區體積接受95%的處方劑量；調彊放射治療與常規切線野治療相比，V110%平均下降9.2%，差異具有統計學意義（P＜0.05）；3例左側乳腺癌患者的心髒V30平均下降3.6%，差異具有統計學意義（P＜0.05）；同側肺V20平均下降8.9%，同側肺V30平均下降11.6%，組間差異均具有統計學意義（P＜0.05）。結論：調彊放射治療可以在保證靶區覆蓋率的基礎上，解決靶區劑量分佈不均勻的問題，減少危及器官尤其是心髒、同側肺的照射劑量和體積。
목적：탐구유선암조강방사치료화상규절선야치료적삼유제량학차이。방법：선취2014년1월지2015년5월아원수치적7례유선암환자，균행보유수술후위기설계조강방사치료화상규절선야치료，병비교량충치료방법재OARs여PTV상적삼유제량학차이。결과：량충방사치료계화적파구복개일치，95%파체적접수50.0Gy적방료제량，99%적파구체적접수95%적처방제량；조강방사치료여상규절선야치료상비，V110%평균하강9.2%，차이구유통계학의의（P＜0.05）；3례좌측유선암환자적심장V30평균하강3.6%，차이구유통계학의의（P＜0.05）；동측폐V20평균하강8.9%，동측폐V30평균하강11.6%，조간차이균구유통계학의의（P＜0.05）。결론：조강방사치료가이재보증파구복개솔적기출상，해결파구제량분포불균균적문제，감소위급기관우기시심장、동측폐적조사제량화체적。
Objective: To compare dosimetry of intensity-modulated radiation therapy and conventional tangential irradiation for breast cancer. Methods: 7 patients with breast cancer were chosen for study which were treated in our hospital between January 2014 and May 2015, a dosimetric comparison about OARs and PTV of intensity-modulated radiation therapy and conventional tangential irradiation was performed on each patient. Results: The PTV coverage in two plans were consistent, the dose of radiation that 95% PTV receieved was 50.0Gy, 99% PTV received 99% prescribed dose; compare to conventional tangential irradiation, V110% in intensity-modulated radiation therapy fell an average of 9.2 percent, V20 and V30 of ipsilateral lung fell an average of 3.6 percent and 8.9 percent respectively, the difference was statistically significant (P<0.05). Conclusion: On the premise of the same PTV coverage, intensity-modulated radiation therapy has a better dose uniformity, and achieve a reduction of irradiation volume and dose at heart and ipsilateral lung.
