CAJ | 학술논문

目的：观察头针配合实时认知功能训练对阿尔茨海默病认知功能障碍患者脑血流的影响。方法将100例阿尔茨海默病认知功能障碍患者随机分为治疗组和对照组，每组50例。两组均给予原基础疾病的治疗，治疗组在此基础上采用头针配合实时认知功能训练治疗，对照组采用口服银杏叶提取物药片治疗。治疗3个月后，采用经颅多普勒检测两组患者治疗前后左侧椎动脉(LVA)、右侧椎动脉(RVA)和大脑中动脉(NCA)的平均流速(Vm)。结果治疗组治疗后LVA、RVA及MCA的Vm与同组治疗前比较，差异均具有统计学意义(P＜0.01)。治疗组治疗后LVA、RVA及MCA的Vm与对照组比较，差异均具有统计学意义(P＜0.05)。结论头针配合实时认知功能训练能改善阿尔茨海默病认知功能障碍患者的脑循环，提高脑血流量。
목적：관찰두침배합실시인지공능훈련대아이자해묵병인지공능장애환자뇌혈류적영향。방법장100례아이자해묵병인지공능장애환자수궤분위치료조화대조조，매조50례。량조균급여원기출질병적치료，치료조재차기출상채용두침배합실시인지공능훈련치료，대조조채용구복은행협제취물약편치료。치료3개월후，채용경로다보륵검측량조환자치료전후좌측추동맥(LVA)、우측추동맥(RVA)화대뇌중동맥(NCA)적평균류속(Vm)。결과치료조치료후LVA、RVA급MCA적Vm여동조치료전비교，차이균구유통계학의의(P＜0.01)。치료조치료후LVA、RVA급MCA적Vm여대조조비교，차이균구유통계학의의(P＜0.05)。결론두침배합실시인지공능훈련능개선아이자해묵병인지공능장애환자적뇌순배，제고뇌혈류량。
Objective To investigate the effect of scalp acupuncture plus real-time cognitive training on cerebral blood flow in Alzheimer disease patients with cognitive disorder.Methods One hundred Alzheimer disease patients with cognitive disorder were randomly allocated to treatment and control groups, 50 cases each. Both groups received treatment for the primary disease. In addition, the treatment group received scalp acupuncture plus real-time cognitive training and the control group took Ginkgo leaf extract tablets. Mean flow velocity (Vm) in the left vertebral artery (LVA), right vertebral artery (RVA) and middle cerebral artery (MCA) were measured using transcranial Doppler in the two groups of patients before and after three months of treatment.Results There were statistically significant pre-/post-treatment differences in LVA, RVA and MCA Vm in the two groups (P<0.01). There were statistically significant post-treatment differences in LVA, RVA and MCA Vm between the treatment and control groups (P<0.05).Conclusions Scalp acupuncture plus real-time cognitive training can improve cerebral circulation and increase cerebral blood flow in Alzheimer disease patients with cognitive disorder.