CAJ | 학술논문

骨骼肌功能障碍作为慢性阻塞性肺疾病最常见的肺外效应之一,是其预后的重要独立因素.能量代谢异常是骨骼肌功能障碍的主要机制之一,本文从线粒体代谢、炎症因子、瘦素等方面对COPD骨骼肌能量代谢进行综述,为开展进一步研究提供依据.
골격기공능장애작위만성조새성폐질병최상견적폐외효응지일,시기예후적중요독립인소.능량대사이상시골격기공능장애적주요궤제지일,본문종선립체대사、염증인자、수소등방면대COPD골격기능량대사진행종술,위개전진일보연구제공의거.
As one of the most common extrapulmonary effects of COPD, skeletal muscle dysfunction is an important independent prognostic factor. The abnormal energy metabolism is one of the main mechanisms of skeletal muscle dysfunction. In this paper, perspective of the mitochondrial metabolism, inflammation factors and leptin, skeletal muscle energy metabolism of patients with COPD were reviewed, in order to provide the basis for further research.