临床医药文献电子杂志
臨床醫藥文獻電子雜誌
림상의약문헌전자잡지
Journal of Clinical Medical Literature (ElectronicEdition)
2015年
28期
5785-5786
,共2页
IP10%PCI%胸痛
IP10%PCI%胸痛
IP10%PCI%흉통
IP10%PCI%Chest pain
目的：探究PCI术后患者发生支架内再狭窄及新发冠脉狭窄时血浆趋化因子干扰素-诱导蛋白10（IP10）水平的差异。方法选取2013年7月～2015年1月因典型胸痛入住潍坊市人民医院心内二科且有冠状动脉支架植入史的冠心病患者66例为研究对象，根据冠脉造影结果分为支架内再狭窄组（22），新发冠脉狭窄组（20）及对照组（24例）。记录三组患者的一般临床资料，分别测定各患者血浆IP10μ?浓度比较各组患者的血浆IP10水平，并分析其与支架内再狭窄的相关性。结果支架内再狭窄组患者血浆IP10水平高于新发冠脉狭窄组（P＜0.05）及对照组（P＜0.05），新发冠脉狭窄组及对照组患者血浆IP10水平差异无统计学意义（P＞0.05），逐步Logistic回归分析显示，血浆IP10水平与PCI术后支架内再狭窄呈正相关（OR=1.108，95%CI 1.021～1.202，P=0.014）。结论 PCI术后支架内再狭窄的患者血浆IP10水平高于新发冠脉狭窄的患者，血浆IP10的水平可以作为鉴别PCI术后患者再发胸痛的生化检测指标之一。
目的：探究PCI術後患者髮生支架內再狹窄及新髮冠脈狹窄時血漿趨化因子榦擾素-誘導蛋白10（IP10）水平的差異。方法選取2013年7月～2015年1月因典型胸痛入住濰坊市人民醫院心內二科且有冠狀動脈支架植入史的冠心病患者66例為研究對象，根據冠脈造影結果分為支架內再狹窄組（22），新髮冠脈狹窄組（20）及對照組（24例）。記錄三組患者的一般臨床資料，分彆測定各患者血漿IP10μ?濃度比較各組患者的血漿IP10水平，併分析其與支架內再狹窄的相關性。結果支架內再狹窄組患者血漿IP10水平高于新髮冠脈狹窄組（P＜0.05）及對照組（P＜0.05），新髮冠脈狹窄組及對照組患者血漿IP10水平差異無統計學意義（P＞0.05），逐步Logistic迴歸分析顯示，血漿IP10水平與PCI術後支架內再狹窄呈正相關（OR=1.108，95%CI 1.021～1.202，P=0.014）。結論 PCI術後支架內再狹窄的患者血漿IP10水平高于新髮冠脈狹窄的患者，血漿IP10的水平可以作為鑒彆PCI術後患者再髮胸痛的生化檢測指標之一。
목적：탐구PCI술후환자발생지가내재협착급신발관맥협착시혈장추화인자간우소-유도단백10（IP10）수평적차이。방법선취2013년7월～2015년1월인전형흉통입주유방시인민의원심내이과차유관상동맥지가식입사적관심병환자66례위연구대상，근거관맥조영결과분위지가내재협착조（22），신발관맥협착조（20）급대조조（24례）。기록삼조환자적일반림상자료，분별측정각환자혈장IP10μ?농도비교각조환자적혈장IP10수평，병분석기여지가내재협착적상관성。결과지가내재협착조환자혈장IP10수평고우신발관맥협착조（P＜0.05）급대조조（P＜0.05），신발관맥협착조급대조조환자혈장IP10수평차이무통계학의의（P＞0.05），축보Logistic회귀분석현시，혈장IP10수평여PCI술후지가내재협착정정상관（OR=1.108，95%CI 1.021～1.202，P=0.014）。결론 PCI술후지가내재협착적환자혈장IP10수평고우신발관맥협착적환자，혈장IP10적수평가이작위감별PCI술후환자재발흉통적생화검측지표지일。
Objective To explore the difference of plasma IP10 level between patients with in-stent restenosis and new coronary artery stenosis after PCI. Methods 66 coronary heart disease inpatients who were hospitalized in our center from July 2013 to January 2015 were selected for research, they all complained chest pain and had accepted stent implantation.They were divided into 3groups according to their CAG results: in-stent restenosis group, new coronary artery stenosis and control group. Their clinical data were recorded and the plasma IP10 level of all the patients were tested and analyzed, and the correlation analysis between plasma IP10 level and in-stent restenosis after PCI was also conducted. Result Compared with new coronary artery stenosis and control group, the plasma IP10 level of patients in in-stent restenosis group was higher (P<0.05). (P>0.05); the difference of plasma IP10 level between patients in new coronary artery stenosis and control group had no Statistical significance (P>0.05).Multivariate regression analysis indicated that the plasma IP10 level was positively correlated to the in-stent restenosis after PCI.Conclusion The plasma IP10 level of patients with in-stent restenosis is higher than that with new coronary artery stenosis after PCI. plasma IP10 level could be one of the indicators used for the differential diagnosis of patients with chest pain after PCI .
