中国药物经济学
中國藥物經濟學
중국약물경제학
China Journal of Pharmaceutical Economics
2015年
11期
179-180
,共2页
重症监护病房%医院感染%耐药性
重癥鑑護病房%醫院感染%耐藥性
중증감호병방%의원감염%내약성
ICU%Nosocomial infection%Drug resistance
目的：对重症监护病房（ICU）送检的病原菌分布及耐药性进行分析，为临床合理用药提供理论依据。方法对2012年12月至2014年3月在辽宁省朝阳市第二医院ICU住院的患者送检标本350份，严格按照美国临床实验室标准化研究所标准进行培养及药敏鉴定，并对实验结果进行分析。结果 ICU住院患者送检标本主要有痰、咽拭子、血、尿、脑脊液、导管、分泌物等，350份标本共分离出病原菌253株，其中革兰阴性菌占62.5%，革兰阳性菌占20.8%。革兰阴性菌主要有铜绿假单胞菌、大肠埃希菌、鲍曼不动菌、肺炎克雷伯菌、阴沟肠杆菌；革兰阳性菌有表皮葡萄球菌、金黄色葡萄球菌、肠球菌等。结论 ICU 感染的病原菌以革兰阴性杆菌为主，革兰阳性球菌为辅。分离到的革兰阴性菌耐药率较高。建议临床有感染的患者及时送检标本，依据细菌鉴定结果合理用药，减少感染及耐药，提高治疗效果。
目的：對重癥鑑護病房（ICU）送檢的病原菌分佈及耐藥性進行分析，為臨床閤理用藥提供理論依據。方法對2012年12月至2014年3月在遼寧省朝暘市第二醫院ICU住院的患者送檢標本350份，嚴格按照美國臨床實驗室標準化研究所標準進行培養及藥敏鑒定，併對實驗結果進行分析。結果 ICU住院患者送檢標本主要有痰、嚥拭子、血、尿、腦脊液、導管、分泌物等，350份標本共分離齣病原菌253株，其中革蘭陰性菌佔62.5%，革蘭暘性菌佔20.8%。革蘭陰性菌主要有銅綠假單胞菌、大腸埃希菌、鮑曼不動菌、肺炎剋雷伯菌、陰溝腸桿菌；革蘭暘性菌有錶皮葡萄毬菌、金黃色葡萄毬菌、腸毬菌等。結論 ICU 感染的病原菌以革蘭陰性桿菌為主，革蘭暘性毬菌為輔。分離到的革蘭陰性菌耐藥率較高。建議臨床有感染的患者及時送檢標本，依據細菌鑒定結果閤理用藥，減少感染及耐藥，提高治療效果。
목적：대중증감호병방（ICU）송검적병원균분포급내약성진행분석，위림상합리용약제공이론의거。방법대2012년12월지2014년3월재요녕성조양시제이의원ICU주원적환자송검표본350빈，엄격안조미국림상실험실표준화연구소표준진행배양급약민감정，병대실험결과진행분석。결과 ICU주원환자송검표본주요유담、인식자、혈、뇨、뇌척액、도관、분비물등，350빈표본공분리출병원균253주，기중혁란음성균점62.5%，혁란양성균점20.8%。혁란음성균주요유동록가단포균、대장애희균、포만불동균、폐염극뢰백균、음구장간균；혁란양성균유표피포도구균、금황색포도구균、장구균등。결론 ICU 감염적병원균이혁란음성간균위주，혁란양성구균위보。분리도적혁란음성균내약솔교고。건의림상유감염적환자급시송검표본，의거세균감정결과합리용약，감소감염급내약，제고치료효과。
Objective To analyze the distribution and drug resistance of pathogens causing nosocomial infections in the intensive care ICU so as to provide reliable theoretical evidence for therational use of drug in clinical practice. Methods The sample col ected from patients hospital in the ICU of the hospital from Decm 2012 to Mar 2014 were retrospectively analyzed.the submitted speciments were cultured.thebacterial indentification was performed.And the results were determined according to the standand of clinical and laboratory standand institute.Meihua120 was adopted to summarize and analyze the relevant date.Results Thespeciments col ected from ICU patients were mainly phlega,blood,csf,urine sample of the 350 speciments.253sample have been cactured strains of gram-negative bacteria accounted for 62.5%,strains of gram-positive bacteria accounted for 20.8%.The top four isolated gram- negative bacteria were Pseudornonas aeruginosa .Escherichia coli,Kcebsieua pneumonia and Acinetobacter baumanni .the gram-postive bacteria were Staphylococcus.Conclusion The pathogents causing ICU infection were mainly gram-negative bacteria,the gram-positive were shortly,most of the isolated gram-negative bacteria had multiple drug resistance.It is necessary to preserve the sample for bacterial indentification intime and to rationly use the drug. accorsing to the drugsensitivity test results in clinical practive so as toeffectively control the nosocomial infections.
