CAJ | 학술논문

伴微乳头结构（micropapillary pattern, MPP）肺腺癌是一种临床少见的具有高度侵袭性的恶性肿瘤，近年来因其高死亡率被人们所重视。2011年关于肺腺癌的病理新分类将其作为一种独立的病理类型，此后针对该类肺癌个体化治疗的相关研究逐渐展开。近期的相关研究发现，伴MPP肺腺癌在转移机制、临床病理学、影像学、治疗及预后方面具有显著异质性。本文对伴MPP肺腺癌转移机制及相关临床研究进展进行探讨。
반미유두결구（micropapillary pattern, MPP）폐선암시일충림상소견적구유고도침습성적악성종류，근년래인기고사망솔피인문소중시。2011년관우폐선암적병리신분류장기작위일충독립적병리류형，차후침대해류폐암개체화치료적상관연구축점전개。근기적상관연구발현，반MPP폐선암재전이궤제、림상병이학、영상학、치료급예후방면구유현저이질성。본문대반MPP폐선암전이궤제급상관림상연구진전진행탐토。
Lung adenocarcinoma with micropapillary pattern (MPP) is a kind of rare high invasive malignant tu-mor, which has been noticed because of high mortality. In 2011, the new pathological classiifcation of lung adenocarcinoma classify it as an independent pathological type, researches on the individual treatment of the disease had been gradually ex-panded. Recent studies have demonstrated that lung adenocarcinoma with MPP has obvious heterogeneities in metastasis mechanism, clinical pathology, imageology, therapeusis and prognosis. In this paper, we discuss the progress of metastasis mechanism and clinical relevance in lung adenocarcinoma with MPP.