CAJ | 학술논문

细胞因子是一类能在细胞间传递信息、发挥免疫调节的蛋白质或小分子多肽；其表达异常诱发多种疾病，包括胃癌。细胞因子参与调控细胞的癌变、侵袭与转移、血管生成，并通过调控肿瘤相关抗原的抗原递呈、淋巴细胞的活化参与胃癌的免疫逃逸，且在胃癌细胞抵抗放化疗治疗中发挥重要作用。因此，调节机体细胞因子的水平，促使机体形成对胃癌的抗肿瘤也就成为胃癌治疗的新方向。
세포인자시일류능재세포간전체신식、발휘면역조절적단백질혹소분자다태；기표체이상유발다충질병，포괄위암。세포인자삼여조공세포적암변、침습여전이、혈관생성，병통과조공종류상관항원적항원체정、림파세포적활화삼여위암적면역도일，차재위암세포저항방화료치료중발휘중요작용。인차，조절궤체세포인자적수평，촉사궤체형성대위암적항종류야취성위위암치료적신방향。
Cytokines are a kind of protein or small molecular peptides and play a role in passing informa-tion between the cells or regulating immune response.The abnormal expressions of cytokines often cause a variety of diseases,including stomach cancer.Cytokines are involved in the regulation of gastric cancer cells carcinogenesis,invasion and metastasis,angiogenesis and immune escape by regulating tumor related antigen presentation and lymphocytes activation.What′s more,cytokines also play an important role in gastric cancer cells resisting radiation and chemotherapy.Therefore,regulation of the body′s cytokines levels to form the antitumor effect of gastric cancer has become a new trend for the treatment of gastric cancer .