CAJ | 학술논문

单肺通气（ OLV）期间吸入纯氧能使动脉血氧分压维持在较高的水平，但也会导致吸收性肺不张和氧中毒。虽然OLV期间降低吸入氧浓度会使低氧血症的发生率增加，但在充分评估围术期患者全身情况下，适当降低吸入氧浓度（ FiO2）能够减轻肺损伤。该文主要描述 OLV 期间氧中毒肺损伤的机制，介绍近年来OLV期间降低FiO2对肺损伤的研究现状。
단폐통기（ OLV）기간흡입순양능사동맥혈양분압유지재교고적수평，단야회도치흡수성폐불장화양중독。수연OLV기간강저흡입양농도회사저양혈증적발생솔증가，단재충분평고위술기환자전신정황하，괄당강저흡입양농도（ FiO2）능구감경폐손상。해문주요묘술 OLV 기간양중독폐손상적궤제，개소근년래OLV기간강저FiO2대폐손상적연구현상。
During one lung ventilation ( OLV) the inhaled 100% O2 can keep arterial oxygen partial pressure(PaO2) at a high level,however it may lead to inhaled atelectasis and oxygen toxicity.Although decreasing FiO2 increased the incidence of hypoxemia during OLV,an intensive perioperative monitoring and appropriate low FiO2 can be helpful to reduce acute lung injury.Here is mainly to describe the mechanisms of pulmonary oxygen toxicity during OLV,and introduce the recent research status of the influence of decreasing FiO2 on lung injury during OLV.