CAJ | 학술논문

作为细胞周期的关键环节，有丝分裂过程受到严格而精细的调控，随着对有丝分裂调控的探讨与拓展，也逐渐加深了人们对生命本质的理解。研究发现Polo 样蛋白激酶1（ PLK1）参与细胞有丝分裂调控的各环节，该文拟归纳总结 Plk1在有丝分裂中诸如 CDK1－Cyclin B 复合物的激活、纺锤体形成、染色体分离和胞质分裂这些过程中的研究进展，并描绘 PLK－1在有丝分裂调控中的作用与意义，为进一步深入探讨PLK－1与有丝分裂调控指出可能的发展方向。
작위세포주기적관건배절，유사분렬과정수도엄격이정세적조공，수착대유사분렬조공적탐토여탁전，야축점가심료인문대생명본질적리해。연구발현Polo 양단백격매1（ PLK1）삼여세포유사분렬조공적각배절，해문의귀납총결 Plk1재유사분렬중제여 CDK1－Cyclin B 복합물적격활、방추체형성、염색체분리화포질분렬저사과정중적연구진전，병묘회 PLK－1재유사분렬조공중적작용여의의，위진일보심입탐토PLK－1여유사분렬조공지출가능적발전방향。
As a crucial part of the cell cycle,the precise regulation of mitosis is precisely and strictly regulated,and along with the exploration in the regulation of mitosis,the understanding of life has deepened gradually as well.Polo-like kinase 1(PIK1) is involved in different processes of mitosis,and here is to sum-marize the functions,such as the activation of CDK1-Cyclin B complex,formation of spindle,segregation of chromosome and cytokinesis,and depict PLK-1′s significance for mitosis and put forward the possible direc-tions of further studies.