医学综述
醫學綜述
의학종술
Medical Recapitulate
2015年
20期
3651-3653,3654
,共4页
王少博(综述)%付正英%张引国(审校)
王少博(綜述)%付正英%張引國(審校)
왕소박(종술)%부정영%장인국(심교)
宫内生长受限%认知障碍%海马
宮內生長受限%認知障礙%海馬
궁내생장수한%인지장애%해마
Intrauterine growth restriction%Cognitive dysfunction%Hippocampus
宫内生长受限( IUGR)是围生期胎儿发病和死亡的主要危险因素之一,它不仅影响胎儿期的生长发育,而且也影响儿童期和青年期的神经系统和体格发育,并与成年后高血压病、冠状动脉粥样硬化性心脏病、糖尿病、肾病等心血管系统以及内分泌系统疾病密切相关。 IUGR损害认知功能的机制目前尚未完全清楚,主要涉及海马结构和功能的变化。
宮內生長受限( IUGR)是圍生期胎兒髮病和死亡的主要危險因素之一,它不僅影響胎兒期的生長髮育,而且也影響兒童期和青年期的神經繫統和體格髮育,併與成年後高血壓病、冠狀動脈粥樣硬化性心髒病、糖尿病、腎病等心血管繫統以及內分泌繫統疾病密切相關。 IUGR損害認知功能的機製目前尚未完全清楚,主要涉及海馬結構和功能的變化。
궁내생장수한( IUGR)시위생기태인발병화사망적주요위험인소지일,타불부영향태인기적생장발육,이차야영향인동기화청년기적신경계통화체격발육,병여성년후고혈압병、관상동맥죽양경화성심장병、당뇨병、신병등심혈관계통이급내분비계통질병밀절상관。 IUGR손해인지공능적궤제목전상미완전청초,주요섭급해마결구화공능적변화。
Intrauterine growth restriction(IUGR),one of the main dangerous factors of perinatal fetal disease and death,not only influences growth and development of fetal period,but also influences the nervous system and physical development of childhood and adolescence.Moreover,it is closely related to diseases of adult cardiovascular system and the endocrine system,such as high blood pressure disease,coronary heart dis-ease,diabetes and kidney disease.Cognitive dysfunction induced by IUGR refers to changes of hippocampal structure and function.Howerever,the mechanism is still unclear,which mainly involves changes in hipp-ocampal formation and function.