CAJ | 학술논문

多种皮肤疾病的发生、演变及预后除与环境、精神心理因素相关外，还与遗传因素密不可分。基因多态性在个体对疾病的易患性、临床表现的多样性及对药物治疗反应的差异性中发挥重要作用，但同一种疾病的基因多态性在不同种族及地域的人群中并不完全一致。该文就中国人群中基因多态性在斑秃、痤疮、染发皮炎、特应性皮炎等疾病中的研究进展进行综述。
다충피부질병적발생、연변급예후제여배경、정신심리인소상관외，환여유전인소밀불가분。기인다태성재개체대질병적역환성、림상표현적다양성급대약물치료반응적차이성중발휘중요작용，단동일충질병적기인다태성재불동충족급지역적인군중병불완전일치。해문취중국인군중기인다태성재반독、좌창、염발피염、특응성피염등질병중적연구진전진행종술。
The occurrence, development and prognosis of various skin diseases are closely related to genetic factors besides environmental factors and psychological factors.Gene polymorphism is viewed as an important contributor to the susceptibilities to some diseases,the varieties of clinical manifestations,and the differences of treatment reactions.Considering the racial and regional differences,the gene polymorphism is not exactly the same between Chinese population and foreign population .Here is to review the main findings of gene polymorphism in alopecia areata,acne,dermatitis in Chinese population.