海峡药学
海峽藥學
해협약학
Strait Pharmaceutical Journal
2015年
10期
88-89
,共2页
压力性尿失禁%索利那新%性功能
壓力性尿失禁%索利那新%性功能
압력성뇨실금%색리나신%성공능
Solifenacin stress urinary incontinence%Sexual function
目的 研究索利那新对女性压力性尿失禁( SUI)患者性功能的影响及相关因素. 方法 2013年12月~2014年5 月接受索利那新治疗的94例患者纳入研究,采用盆腔器官脱垂-尿失禁患者性功能( PISQ-12 )问卷对患者进行随访评分. 结果 81 例( 86.1%)患者回答了PISQ-12问卷,服药前前PISQ总评分为(83.9 ±10.6)min,服药后为(84.6 ±15.3)min,差异无统计学意义(P>0.05). 但服药前后情感因素评分为(27.1 ±10.7)min和(30.5 ±6.7)min,两者比较具有显著性差异(P<0.05). 溢尿组性生活改善率为67.5%(25/37),无溢尿组性生活改善率为22.7%( 10/44 ) ,两者比较,差异有统计学意义( P <0.01 ). 重度组 PISQ 总评分升高率为67.5%( 27/35 ) ,中度组 PISQ 总评分升高率为32.6%(15/46),两者比较,差异有统计学意义(P<0.05). 结论 索利那新对性生活中不自主溢尿者和尿失禁重度患者,服药后症状缓解,可显著提高性生活质量.
目的 研究索利那新對女性壓力性尿失禁( SUI)患者性功能的影響及相關因素. 方法 2013年12月~2014年5 月接受索利那新治療的94例患者納入研究,採用盆腔器官脫垂-尿失禁患者性功能( PISQ-12 )問捲對患者進行隨訪評分. 結果 81 例( 86.1%)患者迴答瞭PISQ-12問捲,服藥前前PISQ總評分為(83.9 ±10.6)min,服藥後為(84.6 ±15.3)min,差異無統計學意義(P>0.05). 但服藥前後情感因素評分為(27.1 ±10.7)min和(30.5 ±6.7)min,兩者比較具有顯著性差異(P<0.05). 溢尿組性生活改善率為67.5%(25/37),無溢尿組性生活改善率為22.7%( 10/44 ) ,兩者比較,差異有統計學意義( P <0.01 ). 重度組 PISQ 總評分升高率為67.5%( 27/35 ) ,中度組 PISQ 總評分升高率為32.6%(15/46),兩者比較,差異有統計學意義(P<0.05). 結論 索利那新對性生活中不自主溢尿者和尿失禁重度患者,服藥後癥狀緩解,可顯著提高性生活質量.
목적 연구색리나신대녀성압력성뇨실금( SUI)환자성공능적영향급상관인소. 방법 2013년12월~2014년5 월접수색리나신치료적94례환자납입연구,채용분강기관탈수-뇨실금환자성공능( PISQ-12 )문권대환자진행수방평분. 결과 81 례( 86.1%)환자회답료PISQ-12문권,복약전전PISQ총평분위(83.9 ±10.6)min,복약후위(84.6 ±15.3)min,차이무통계학의의(P>0.05). 단복약전후정감인소평분위(27.1 ±10.7)min화(30.5 ±6.7)min,량자비교구유현저성차이(P<0.05). 일뇨조성생활개선솔위67.5%(25/37),무일뇨조성생활개선솔위22.7%( 10/44 ) ,량자비교,차이유통계학의의( P <0.01 ). 중도조 PISQ 총평분승고솔위67.5%( 27/35 ) ,중도조 PISQ 총평분승고솔위32.6%(15/46),량자비교,차이유통계학의의(P<0.05). 결론 색리나신대성생활중불자주일뇨자화뇨실금중도환자,복약후증상완해,가현저제고성생활질량.
OBJECTIVE To evaluate postoperative effects of solifenacin on sexual function of female patients with genuine stress urinary incontinence.METHODS 94 sexually active patients who underwent TVT-O procedure between December 2013 and May 2014 in our urological center were included in this study.During the follow-up pe-riod,they were evaluated their sexual function with the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-12 ( PISQ-12 ) .RESULTS 81 patients ( 86.1%) completed the questionnaire.The total average scores of PISQ-12 were (85.3 ±10.6) min and (84.6 ±16.5) min before and after treat,respectively,and there was no significant difference(P>0.05);however,the behavioral emotional domain scores increased significantly from (27.1 ±10.7) min to (30.5 ±6.7)min(P<0.05);The sexual function improvement rats were 67.5%(37/49)and 22.7%(9/35 ) in patients with and without urine leakage during sexual intercourse,respectively.Similarly,most of patients with serious SUI could get sexual function improvement.CONCLUSION The patients with involuntary urine leakage during sexual intercourse or serious symptom may improve their sexual function due to the leakage alleviation.
