海峡药学
海峽藥學
해협약학
Strait Pharmaceutical Journal
2015年
10期
85-87
,共3页
银杏达莫%奥扎格雷钠%急性脑梗死
銀杏達莫%奧扎格雷鈉%急性腦梗死
은행체막%오찰격뢰납%급성뇌경사
Yinxingdamo%Ozagrel%Acute cerebral infarction
目的 探讨银杏达莫注射液联合奥扎格雷钠注射液治疗急性脑梗死(Acutecerebralinfarction,ACI)临床疗效.方法 156例ACI患者按就诊顺序1:1比例随机分为治疗组和对照组,各78例. 两组患者均给予常规综合治疗,治疗组加用银杏达莫注射液20 mL稀释后静脉滴注,奥扎格雷钠氯化钠注射液80mg(100mL)静脉滴注,均1日1次;对照组加用复方丹参20mL稀释后静脉滴注,胞二磷胆碱1.0稀释后静脉滴注,均1日1次.两组疗程均为10d.结果 ①治疗组总有效率为92.3%(72/78),对照组总有效率为80.8%(63/78),治疗组治疗效果明显优于对照组(P<0.05);②治疗后治疗组DNDS改善明显优于对照组(P<0.01);③治疗组治疗后 DNDS明显低于治疗前(P<0.01). 结论 银杏达莫注射液联合奥扎格雷钠注射液治疗ACI具有疗效确切、安全可靠、副作用少等优点,值得临床推广使用.
目的 探討銀杏達莫註射液聯閤奧扎格雷鈉註射液治療急性腦梗死(Acutecerebralinfarction,ACI)臨床療效.方法 156例ACI患者按就診順序1:1比例隨機分為治療組和對照組,各78例. 兩組患者均給予常規綜閤治療,治療組加用銀杏達莫註射液20 mL稀釋後靜脈滴註,奧扎格雷鈉氯化鈉註射液80mg(100mL)靜脈滴註,均1日1次;對照組加用複方丹參20mL稀釋後靜脈滴註,胞二燐膽堿1.0稀釋後靜脈滴註,均1日1次.兩組療程均為10d.結果 ①治療組總有效率為92.3%(72/78),對照組總有效率為80.8%(63/78),治療組治療效果明顯優于對照組(P<0.05);②治療後治療組DNDS改善明顯優于對照組(P<0.01);③治療組治療後 DNDS明顯低于治療前(P<0.01). 結論 銀杏達莫註射液聯閤奧扎格雷鈉註射液治療ACI具有療效確切、安全可靠、副作用少等優點,值得臨床推廣使用.
목적 탐토은행체막주사액연합오찰격뢰납주사액치료급성뇌경사(Acutecerebralinfarction,ACI)림상료효.방법 156례ACI환자안취진순서1:1비례수궤분위치료조화대조조,각78례. 량조환자균급여상규종합치료,치료조가용은행체막주사액20 mL희석후정맥적주,오찰격뢰납록화납주사액80mg(100mL)정맥적주,균1일1차;대조조가용복방단삼20mL희석후정맥적주,포이린담감1.0희석후정맥적주,균1일1차.량조료정균위10d.결과 ①치료조총유효솔위92.3%(72/78),대조조총유효솔위80.8%(63/78),치료조치료효과명현우우대조조(P<0.05);②치료후치료조DNDS개선명현우우대조조(P<0.01);③치료조치료후 DNDS명현저우치료전(P<0.01). 결론 은행체막주사액연합오찰격뢰납주사액치료ACI구유료효학절、안전가고、부작용소등우점,치득림상추엄사용.
OBJECTIVE To evaluate the clinical efficacy of Yinxingdamo injection combined with ozagrel sodi-uminjectioninthetreatmentofacutecerebralinfarction(ACI).METHODS 156casesofACIpatientsaccording to the order of the ratio of 1:1 were randomly divided into treatment group and control group,78 cases in each.Two groups of patients were given conventional therapy,the treatment group were further treated with ginkgo leaf extract and dipyridamole injection 20mL diluted intravenous drip, 80mg ozagrel sodium and sodium chloride injection (100mL) intravenous injection,1 times daily;the control group were further treated with Compound Danshen 20mL diluted intravenous drip, citicoline 1.0 diluted intravenous drip, 1 times daily.Two groups were treated for 10d.RESULTS ①Thetreatmentgrouptotaleffectiveratewas92.3%(72/78)thecontrolgrouptotaleffectiverate was 80.8%(63/78),treatment group was better than the control group (P<0.05);②After treatment,DNDS of treatment group improved significantly better than the control group ( P<0.01);③After treatment,DNDS was signif-icantly lower than that before treatment ( P<0.01 ) .CONCLUSION Ginkgo leaf extract and dipyridamole injec-tion combined with ozagrel sodium injection in the treatment of acute cerebral infarction has the advantages of exact curative effect,safety and side effects less,which is worthy of clinical use.
