蚌埠医学院学报
蚌埠醫學院學報
방부의학원학보
Journal of Bengbu Medical College
2015年
11期
1496-1499,1500
,共5页
糖尿病%糖尿病足%溃疡%危险因素%纤维蛋白原%胱抑素C%脂蛋白a
糖尿病%糖尿病足%潰瘍%危險因素%纖維蛋白原%胱抑素C%脂蛋白a
당뇨병%당뇨병족%궤양%위험인소%섬유단백원%광억소C%지단백a
diabetes mellitus%diabetic foot%ulcers%risk factors%fibrinogen%cystatin C%lipoprotein( a)
目的：：探讨糖尿病足( dibatic foot,DF)溃疡发生的危险因素,为预防及延缓DF溃疡的发生、发展提供参考依据。方法：收集DF溃疡住院患者201例,糖尿病无 DF 溃疡住院患者302例。对相关临床资料、实验室检测指标进行分析。结果：Logistic回归分析提示,男性、诊断时间、红细胞沉降率、纤维蛋白原、C反应蛋白、胱抑素C、糖化血红蛋白和脂蛋白( a)均为DF溃疡的危险因素(P<0.05~P<0.01)。其中男性、诊断时间、红细胞沉降率、C反应蛋白、胱抑素C均为独立危险因素(P<0.05~P<0.01)。结论：对于有危险因素的或已经发现糖尿病或DF溃疡的患者,应该积极控制血糖,合理抗感染、抗凝、降纤维蛋白原以及适当的营养支持等综合治疗。
目的：：探討糖尿病足( dibatic foot,DF)潰瘍髮生的危險因素,為預防及延緩DF潰瘍的髮生、髮展提供參攷依據。方法：收集DF潰瘍住院患者201例,糖尿病無 DF 潰瘍住院患者302例。對相關臨床資料、實驗室檢測指標進行分析。結果：Logistic迴歸分析提示,男性、診斷時間、紅細胞沉降率、纖維蛋白原、C反應蛋白、胱抑素C、糖化血紅蛋白和脂蛋白( a)均為DF潰瘍的危險因素(P<0.05~P<0.01)。其中男性、診斷時間、紅細胞沉降率、C反應蛋白、胱抑素C均為獨立危險因素(P<0.05~P<0.01)。結論：對于有危險因素的或已經髮現糖尿病或DF潰瘍的患者,應該積極控製血糖,閤理抗感染、抗凝、降纖維蛋白原以及適噹的營養支持等綜閤治療。
목적：：탐토당뇨병족( dibatic foot,DF)궤양발생적위험인소,위예방급연완DF궤양적발생、발전제공삼고의거。방법：수집DF궤양주원환자201례,당뇨병무 DF 궤양주원환자302례。대상관림상자료、실험실검측지표진행분석。결과：Logistic회귀분석제시,남성、진단시간、홍세포침강솔、섬유단백원、C반응단백、광억소C、당화혈홍단백화지단백( a)균위DF궤양적위험인소(P<0.05~P<0.01)。기중남성、진단시간、홍세포침강솔、C반응단백、광억소C균위독립위험인소(P<0.05~P<0.01)。결론：대우유위험인소적혹이경발현당뇨병혹DF궤양적환자,응해적겁공제혈당,합리항감염、항응、강섬유단백원이급괄당적영양지지등종합치료。
Objective:To explore the risk factors for diabetic foot(DF) ulcers and provide reference for the prevention and delay of the occurrence of DF ulcers. Methods:Two hundred and one cases of hospitalized patients with DF ulcers and 302 cases with non-DF ulcers were collected in the study. SPSS 22. 0 software was used for statistical analysis of the related dinical data and laboratory fest index. Results:Logistic regression analysis showed that male, levels of erythrocyte sedimentation rate, fibrinogen, C-reactive protein, cystatin C,glycated hemoglobin,lipoprotein(a)and uric acid were the risk factors for DF ulcers(P<0. 05 to P<0. 01),among which male,diagnosis time,levels of erythrocyte sedimentation rate,C-reactive protein and cystatin C were independent risk factors(P<0. 05 to P<0. 01). Conclusions:Comprehensive treatment including control of blood glucose, anti-infection, anticoagulant, fibrinolysis and proper nutrition support are essential for patients with diabetes or diabetic foot ulcer.
