CAJ | 학술논문

目的：合成5-氧-烯丙基-2，3，4-三-氧-苄基- D -核糖醇。方法以 D -核糖为原料，经甲苷化、苄基化、水解、肟保护、烯丙基化、脱肟、还原7步反应得到5-氧-烯丙基-2，3，4-三-氧-苄基- D -核糖醇。结果与讨论总收率55%，目标产物结构经核磁共振氢谱确认。该合成路线步骤少，绿色环保，适合工业化生产。
목적：합성5-양-희병기-2，3，4-삼-양-변기- D -핵당순。방법이 D -핵당위원료，경갑감화、변기화、수해、우보호、희병기화、탈우、환원7보반응득도5-양-희병기-2，3，4-삼-양-변기- D -핵당순。결과여토론총수솔55%，목표산물결구경핵자공진경보학인。해합성로선보취소，록색배보，괄합공업화생산。
Objective To synthesize 5 - allyloxy - 2,3,4 - tris(benzyloxy)pentan - 1 - ol. Methods With D - ri-bose as the starting material,5 - allyloxy - 2,3,4 - tris(benzyloxy)pentan - 1 - ol was obtained by glycosidation,benzyla-tion,hydrolyzation,oxime protection,allylation,deoximation and reduction. Results and Conclusion The overall yield of this method was 55% ,and the structure of product was characterized by 1H - NMR. The synthetic route was short and envi-ronmentally friendly,suitable for the industrial production.