中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
11期
1477-1479,1480
,共4页
万古霉素%合理用药%适应证
萬古黴素%閤理用藥%適應證
만고매소%합리용약%괄응증
Vancomycin%Rational medication%Indications
目的：评价南京市高淳人民医院（以下简称“我院”）的临床万古霉素应用合理性。方法：采用回顾性调查方法，对2012年9月—2014年9月住院患者应用万古霉素合理性进行分析。结果：176例患者中，治疗用药172例，预防用药4例。病例分布最多的科室为脑外科、重症监护中心、呼吸内科。有166例应用万古霉素之前进行了病原学检查，送检的样本只有100例成功分离病菌，45例对万古霉素敏感。合理用药的32例，基本合理用药10例，不合理用药134例，其中涉及用药时间过长27例。结论：我院对应用万古霉素所需的病原学检查与肝、肾功能监测都很重视，但对应用万古霉素较多的混合感染的重症患者，肾功能不全患者或是老年患者，病原学检查缺乏针对性。对此，应加强对万古霉素应用指导，血药浓度监测、病原学监测的力度，提高万古霉素合理用药水平。
目的：評價南京市高淳人民醫院（以下簡稱“我院”）的臨床萬古黴素應用閤理性。方法：採用迴顧性調查方法，對2012年9月—2014年9月住院患者應用萬古黴素閤理性進行分析。結果：176例患者中，治療用藥172例，預防用藥4例。病例分佈最多的科室為腦外科、重癥鑑護中心、呼吸內科。有166例應用萬古黴素之前進行瞭病原學檢查，送檢的樣本隻有100例成功分離病菌，45例對萬古黴素敏感。閤理用藥的32例，基本閤理用藥10例，不閤理用藥134例，其中涉及用藥時間過長27例。結論：我院對應用萬古黴素所需的病原學檢查與肝、腎功能鑑測都很重視，但對應用萬古黴素較多的混閤感染的重癥患者，腎功能不全患者或是老年患者，病原學檢查缺乏針對性。對此，應加彊對萬古黴素應用指導，血藥濃度鑑測、病原學鑑測的力度，提高萬古黴素閤理用藥水平。
목적：평개남경시고순인민의원（이하간칭“아원”）적림상만고매소응용합이성。방법：채용회고성조사방법，대2012년9월—2014년9월주원환자응용만고매소합이성진행분석。결과：176례환자중，치료용약172례，예방용약4례。병례분포최다적과실위뇌외과、중증감호중심、호흡내과。유166례응용만고매소지전진행료병원학검사，송검적양본지유100례성공분리병균，45례대만고매소민감。합리용약적32례，기본합리용약10례，불합리용약134례，기중섭급용약시간과장27례。결론：아원대응용만고매소소수적병원학검사여간、신공능감측도흔중시，단대응용만고매소교다적혼합감염적중증환자，신공능불전환자혹시노년환자，병원학검사결핍침대성。대차，응가강대만고매소응용지도，혈약농도감측、병원학감측적력도，제고만고매소합리용약수평。
OBJECTIVE:To evaluate the application rationality of clinical vancomycin in People's Hospital of Nanjing Gaochun (hereinafter referred to as “our hospital”).METHODS:Retrospective investigation was applied into the analysis of application rationality of clinical vancomycin for inpatients from Sept .2012 to Sept.2014.RESULTS: Of the total 176 cases, 172 cases received therapeutic medication and 4 cases received preventive medication .The departments with most cases of distribution were department of cerebral surgery , ICU and respiratory medicine .There were 166 cases had the test of pathogeny before the application of vancomycin;of the tested samples , only 100 cases had the successful isolation of pathogenic bacteria and 45 cases were sensitive to vancomycin .There were 32 cases with rational drug use , 10 cases with basically rational drug use and 134 cases with irrational drug use , among which 27 cases with overlong time of drug use . CONCLUSIONS:Our hospital attaches importance to the test of pathogeny and monitoring of liver and kidney function that needed in the application of vancomycin , but still lacks of specific evaluation on the test of pathogeny in mixed infection critical patients, chronic renal failure patients or the elderly patients with a large application amount of vancomycin . Therefore, it is necessary to strenghen the application guidance of vancomycin , mornitoring of blood concentration and mornitoring strength of etiology , so as to improve the level of rational application of vancomycin .
