中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
11期
1447-1448,1449
,共3页
氢溴酸右美沙芬胶囊%富马酸阿奇霉素%慢性咽炎%安全性
氫溴痠右美沙芬膠囊%富馬痠阿奇黴素%慢性嚥炎%安全性
경추산우미사분효낭%부마산아기매소%만성인염%안전성
Dextromethorphan hydrobromide capsules%Fumaric acid azithromycin%Chronic pharyngitis%Safety
目的：探讨氢溴酸右美沙芬胶囊配伍富马酸阿奇霉素治疗慢性咽炎的疗效和安全性。方法：选择荆州市第二人民医院2012年4月—2014年10月收治156例慢性咽炎患者作为研究对象，按随机数字表法分为观察组和对照组各78例。对照组患者应用富马酸阿奇霉素治疗，观察组患者在对照组治疗的基础上加用氢溴酸右美沙芬胶囊，观察2组患者的疗效及不良反应发生情况。结果：观察组患者的总有效率为92.31％（72／78），对照组患者的总有效率为74.36％（58／78），2组的差异有统计学意义（ P＜0.05）；观察组患者的不良反应发生率为12.82％（10／78），对照组为10.26％（8／78），2组的差异无统计学意义（ P＞0.05）。结论：氢溴酸右美沙芬胶囊配伍富马酸阿奇霉素治疗慢性咽炎可有效消除咽部炎症反应，缓解咽部不适，且不良反应少，值得临床推广。
目的：探討氫溴痠右美沙芬膠囊配伍富馬痠阿奇黴素治療慢性嚥炎的療效和安全性。方法：選擇荊州市第二人民醫院2012年4月—2014年10月收治156例慢性嚥炎患者作為研究對象，按隨機數字錶法分為觀察組和對照組各78例。對照組患者應用富馬痠阿奇黴素治療，觀察組患者在對照組治療的基礎上加用氫溴痠右美沙芬膠囊，觀察2組患者的療效及不良反應髮生情況。結果：觀察組患者的總有效率為92.31％（72／78），對照組患者的總有效率為74.36％（58／78），2組的差異有統計學意義（ P＜0.05）；觀察組患者的不良反應髮生率為12.82％（10／78），對照組為10.26％（8／78），2組的差異無統計學意義（ P＞0.05）。結論：氫溴痠右美沙芬膠囊配伍富馬痠阿奇黴素治療慢性嚥炎可有效消除嚥部炎癥反應，緩解嚥部不適，且不良反應少，值得臨床推廣。
목적：탐토경추산우미사분효낭배오부마산아기매소치료만성인염적료효화안전성。방법：선택형주시제이인민의원2012년4월—2014년10월수치156례만성인염환자작위연구대상，안수궤수자표법분위관찰조화대조조각78례。대조조환자응용부마산아기매소치료，관찰조환자재대조조치료적기출상가용경추산우미사분효낭，관찰2조환자적료효급불량반응발생정황。결과：관찰조환자적총유효솔위92.31％（72／78），대조조환자적총유효솔위74.36％（58／78），2조적차이유통계학의의（ P＜0.05）；관찰조환자적불량반응발생솔위12.82％（10／78），대조조위10.26％（8／78），2조적차이무통계학의의（ P＞0.05）。결론：경추산우미사분효낭배오부마산아기매소치료만성인염가유효소제인부염증반응，완해인부불괄，차불량반응소，치득림상추엄。
OBJECTIVE:To explore the efficacy and safety of Dextromethorphan hydrobromide capsules and fumaric acid azithromycin in treatment of chronic pharyngitis .METHODS:156 patients with chronic pharyngitis admitted into the Second People's Hospital of Jingzhou from Apr .2013 to Oct.2014 were selected as the research objects , who were divided into observation group and control group via the random number table , with 78 cases in each group .The control group were treated with fumaric acid azithromycin , while the observation group additionally received Dextromethorphan hydrobromide capsules based on the control group .The total effect and incidence of adverse reactions of the two groups were observed .RESULTS:The total effective rate of observation group was higher than that of control group [ (92.31%, 72/78)VS (74.4%,58/78], the difference was statistically significant (P<0.05).Also, the incidence of adverse reactions in observation group was 12.82%(10/78), and in control group was 10.26%(8/78),there were no significant difference between two groups ( P>0.05 ) .CONCLUSIONS: Dextromethorphan hydrobromide capsules combined with azithromycin fumarate in treatment of chronic pharyngitis can effectively eliminate the pharyngeal inflammation and relieve throat discomfort with few adverse reactions , it is worthy of clinical promotion .
