CAJ | 학술논문

目的通过对沭阳县部分健康孕妇与健康非孕妇女血清尿素氮(BUN)、肌酐(Cr)、胱抑素C(CYS-C)的测定,探讨该地区健康孕妇血清BUN、Cr、CYS-C的健康参考范围,为临床诊断提供依据.方法选择在我院建孕期保健卡并生产的资料完整孕妇198例,按照建卡期和待产期两个时间段作为研究对象,选取30例年龄相仿未孕健康女性作为对照组,采用常规化学法对上述指标进行检测分析,比较各组上述指标的差异.结果调查所用的检测系统精密度、准确度良好.健康孕妇血清BUN、Cr含量与非孕妇相比偏低,差异有统计学意义(P＜0.05),不同孕期相比差异无统计学意义(P＞0.05).健康孕妇血清CYS-Cr含量与非孕相比偏高,差异有统计学意义(P＜0.05),不同孕期相比差异有统计学意义(P＜0.05).建卡期参考区间为0.56 ～ 1.4 mg/L,待产期参考区间为0.61 ～ 1.77 mg/L.结论针对沭阳县孕妇的实际情况,建立了不同的BUN、Cr、CYS-C参考区间.
목적 통과대술양현부분건강잉부여건강비잉부녀혈청뇨소담(BUN)、기항(Cr)、광억소C(CYS-C)적측정,탐토해지구건강잉부혈청BUN、Cr、CYS-C적건강삼고범위,위림상진단제공의거.방법 선택재아원건잉기보건잡병생산적자료완정잉부198례,안조건잡기화대산기량개시간단작위연구대상,선취30례년령상방미잉건강녀성작위대조조,채용상규화학법대상술지표진행검측분석,비교각조상술지표적차이.결과 조사소용적검측계통정밀도、준학도량호.건강잉부혈청BUN、Cr함량여비잉부상비편저,차이유통계학의의(P＜0.05),불동잉기상비차이무통계학의의(P＞0.05).건강잉부혈청CYS-Cr함량여비잉상비편고,차이유통계학의의(P＜0.05),불동잉기상비차이유통계학의의(P＜0.05).건잡기삼고구간위0.56 ～ 1.4 mg/L,대산기삼고구간위0.61 ～ 1.77 mg/L.결론 침대술양현잉부적실제정황,건립료불동적BUN、Cr、CYS-C삼고구간.
Objective To explore the reference intervals of BUN, Cr, CYS-C in healthy gravidas at Shuyang.Merhods 198 gravidas with complete data built pregnancy care card and deliver at our hospital were selected and were divided into a card-making period group and a delivery-waiting period group according to duration of pregnancy.30 healthy un-pregnant women with the same age were selected as a control group.The renal function indexes were detected using routine methods and then were compared between these three groups.Results The detection systems were accurate and precise.The BUN and Cr levels were lower and CYS-C level was higher in healthy pregnant than un-pregnant women, with statistical differences(P＞0.05).There were no statistical differences in BUN and Cr levels(P＜0.05) but there was in CYS-C level (P＜0.05) between gravidas in different durations of pregnancy.The reference intervals was 0.56-1.40 mg/L in the card-making period group and 0.61-1.77 mg/L in the delivery-waiting period.Conclusions The different reference intervals of BUN, Cr, and CYS-C were set according to the situation of the gravidas at Shuyang.