CAJ | 학술논문

目的探讨开放性鼓室成形术后术腔真菌感染的临床特征及不同治疗方法.方法分析2013年1月至2014年11月乳突术腔真菌感染45例患者(45耳)的临床特征、菌群分布,耳内镜清理术腔真菌病变后,将患者随机分为硼酸酒精组(20耳)和派瑞松乳膏组(25耳)进行疗效对比.结果真菌培养多为曲霉菌,常合并细菌感染.治疗后4周,涂用派瑞松乳膏组痊愈22例,有效3例,无效0例,总有效率为100％,半年后复发4例,复发率16％;硼酸酒精组痊愈9例,有效6例,无效5例,总有效率为75％,半年后复发12例,复发率60％.两组治疗有效率和复发率比较,差异有统计学意义.结论开放式鼓室成形术后再感染原因真菌感染常见,治疗方案采用耳内镜清理后涂用派瑞松乳膏疗效明显优于局部滴硼酸酒精,复发率低.
목적 탐토개방성고실성형술후술강진균감염적림상특정급불동치료방법.방법 분석2013년1월지2014년11월유돌술강진균감염45례환자(45이)적림상특정、균군분포,이내경청리술강진균병변후,장환자수궤분위붕산주정조(20이)화파서송유고조(25이)진행료효대비.결과 진균배양다위곡매균,상합병세균감염.치료후4주,도용파서송유고조전유22례,유효3례,무효0례,총유효솔위100％,반년후복발4례,복발솔16％;붕산주정조전유9례,유효6례,무효5례,총유효솔위75％,반년후복발12례,복발솔60％.량조치료유효솔화복발솔비교,차이유통계학의의.결론 개방식고실성형술후재감염원인진균감염상견,치료방안채용이내경청리후도용파서송유고료효명현우우국부적붕산주정,복발솔저.
Objective To analyze the clinical features and different treatment methods of fungal infection in surgical cavity after canal wall down tympanoplasty.Methods The clinical characteristics and fugal flora distribution of 45 patients (45 ears) with fungal infection in surgical mastoid cavity enrolled from January, 2013 to November, 2014 were analyzed.The fungal infectious lesion in surgical cavity was cleared under otoendoscope.Then, the patients were divided into a boric acid alcohol group (20 ears) and a pevisone cream group (25 ears).The treatment efficacies were compared between these two groups.Results Fugal cultures mainly found aspergillus.Most the patients complicated with bacteria infection.4 weeks after the treatment, 22 ears were cured, 3 responsed well, none didn't response, the total efficacy was 100％, and 4 (16％) re-occurred half year from then in the pevisone cream group and 9 were cured, 6 responsed well, 5 didn't responsed, the total efficacy was 75％, and 12 (60％) re-occurred half year from then in the boric acid alcohol group.There were statistical differences in total efficacy and recurrence rate between these two groups.Conclusions Fungal infection commonly occurs after canal wall down tympanoplasty.Otoendoscopic treatment combined pevisone cream is better than with boric acid alcohol and has a lower recurrence rate.