国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
International Medicine and Health Guidance News
2015年
21期
3189-3192
,共4页
参附注射液%西药%急性心力衰竭%血浆NT-proBNP%心功能
參附註射液%西藥%急性心力衰竭%血漿NT-proBNP%心功能
삼부주사액%서약%급성심력쇠갈%혈장NT-proBNP%심공능
Shenfu injection%Western medicine%Acute heart failure%Plasma NT-proBNP%Cardiac function
目的 探讨参附注射液联合西药治疗急性心力衰竭患者的疗效及对血浆NT-proBNP和心功能的影响.方法 纳入2013年1月至2015年1月于我院接受诊治的心力衰竭患者89例.随机分为实验组(n=46)和对照组(n=43).实验组采用参附注射液联合西药治疗,对照组采用西药治疗.两组均以1周为1疗程,连续治疗2疗程.结果 实验组总有效率(89.13％)明显高于对照组(66.44％)(P＜0.05);实验组和对照组LVEF治疗后明显高于治疗前(P＜0.05),而CVP治疗后明显低于治疗前(P＜0.05);治疗后,实验组LVEF明显高于对照组(P＜0.05),而CVP明显低于对照组(P＜0.05);实验组和对照组血浆NT-proBNP治疗后明显低于治疗前(P＜0.05);治疗后实验组血浆NT-pwBNP明显低于对照组(P＜0.05);在药物治疗期间两组患者均未出现明显不良反应.结论 参附注射液联合西药治疗急性心力衰竭患者疗效明显,可显著降低患者血浆NT-pwBNP水平,改善心功能.
目的 探討參附註射液聯閤西藥治療急性心力衰竭患者的療效及對血漿NT-proBNP和心功能的影響.方法 納入2013年1月至2015年1月于我院接受診治的心力衰竭患者89例.隨機分為實驗組(n=46)和對照組(n=43).實驗組採用參附註射液聯閤西藥治療,對照組採用西藥治療.兩組均以1週為1療程,連續治療2療程.結果 實驗組總有效率(89.13％)明顯高于對照組(66.44％)(P＜0.05);實驗組和對照組LVEF治療後明顯高于治療前(P＜0.05),而CVP治療後明顯低于治療前(P＜0.05);治療後,實驗組LVEF明顯高于對照組(P＜0.05),而CVP明顯低于對照組(P＜0.05);實驗組和對照組血漿NT-proBNP治療後明顯低于治療前(P＜0.05);治療後實驗組血漿NT-pwBNP明顯低于對照組(P＜0.05);在藥物治療期間兩組患者均未齣現明顯不良反應.結論 參附註射液聯閤西藥治療急性心力衰竭患者療效明顯,可顯著降低患者血漿NT-pwBNP水平,改善心功能.
목적 탐토삼부주사액연합서약치료급성심력쇠갈환자적료효급대혈장NT-proBNP화심공능적영향.방법 납입2013년1월지2015년1월우아원접수진치적심력쇠갈환자89례.수궤분위실험조(n=46)화대조조(n=43).실험조채용삼부주사액연합서약치료,대조조채용서약치료.량조균이1주위1료정,련속치료2료정.결과 실험조총유효솔(89.13％)명현고우대조조(66.44％)(P＜0.05);실험조화대조조LVEF치료후명현고우치료전(P＜0.05),이CVP치료후명현저우치료전(P＜0.05);치료후,실험조LVEF명현고우대조조(P＜0.05),이CVP명현저우대조조(P＜0.05);실험조화대조조혈장NT-proBNP치료후명현저우치료전(P＜0.05);치료후실험조혈장NT-pwBNP명현저우대조조(P＜0.05);재약물치료기간량조환자균미출현명현불량반응.결론 삼부주사액연합서약치료급성심력쇠갈환자료효명현,가현저강저환자혈장NT-pwBNP수평,개선심공능.
Objective To investigate the clinical efficacy of Shenfu injection combined with western medicine in the treatment of patients with acute heart failure and its effects on plasma NT-proBNP and cardiac function.Methods 89 patients with heart failure treated at our hospital from January, 2013 to January, 2015 were randomly divided into an experimental group (n=46) and a control group (n=43).The experimental group were treated with Shenfu injection and western medicine and the control group only with western medicine.The treatment course were 2 weeks.Results The total efficacy was significantly higher in the experimental group than in the control group (89.13％ vs.66.44％, P＜0.05).The LVEF was significantly higher and the CVP and plasma NT-proBNP were significantly lower after than before the treatment in both groups (P＜0.05).After the treatment, the LVEF was significantly higher and the CVP and plasma NT-proBNP were significantly lower in the experimental group than in the control group (P＜0.05).No significantly adverse reactions occurred in both groups during the treatment.Conclusions Shenfu injection combined with western medicine in the treatment of patients with acute heart failure is obviously effective and can significantly lower plasma NT-proBNP levels and improve cardiac function.
