国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
International Medicine and Health Guidance News
2015年
22期
3321-3323
,共3页
高钠%ICU%连续血液净化
高鈉%ICU%連續血液淨化
고납%ICU%련속혈액정화
Hypernatronemia%Intensive care unit%Continuous blood purification
目的 观察连续血液净化治疗ICU内高钠血症患者的临床疗效.方法 96例ICU内高钠血症患者按照治疗方式不同分为对照组与治疗组各48例.对照组采用常规保守治疗,治疗组于对照组治疗基础上采用连续血液净化治疗.观察两组患者治疗前后血钠浓度、肌酐、尿素氮、血浆渗透压、心率、平均动脉压变化,预后.结果 治疗后,两组患者血钠浓度、肌酐、尿素氮、血浆渗透压较治疗前均明显下降,但治疗组下降更显著(P＜0.05);两组患者平均动脉压较治疗前均明显升高,但治疗组升高更显著(P＜0.05).随访1年,治疗组分别治愈及存活22例(45.83％)、43例(89.58％),明显高于对照组的13例(27.08％)、31例(64.58％),差异有统计学意义(x2=6.75,8.96;P＜ 0.05).结论 临床采用连续血液净化治疗ICU内高钠患者,可显著降低其血钠浓度,并有效改善其肾功能及血浆渗透压,逐步稳定其生命体征,提高临床疗效,从而改善预后.
目的 觀察連續血液淨化治療ICU內高鈉血癥患者的臨床療效.方法 96例ICU內高鈉血癥患者按照治療方式不同分為對照組與治療組各48例.對照組採用常規保守治療,治療組于對照組治療基礎上採用連續血液淨化治療.觀察兩組患者治療前後血鈉濃度、肌酐、尿素氮、血漿滲透壓、心率、平均動脈壓變化,預後.結果 治療後,兩組患者血鈉濃度、肌酐、尿素氮、血漿滲透壓較治療前均明顯下降,但治療組下降更顯著(P＜0.05);兩組患者平均動脈壓較治療前均明顯升高,但治療組升高更顯著(P＜0.05).隨訪1年,治療組分彆治愈及存活22例(45.83％)、43例(89.58％),明顯高于對照組的13例(27.08％)、31例(64.58％),差異有統計學意義(x2=6.75,8.96;P＜ 0.05).結論 臨床採用連續血液淨化治療ICU內高鈉患者,可顯著降低其血鈉濃度,併有效改善其腎功能及血漿滲透壓,逐步穩定其生命體徵,提高臨床療效,從而改善預後.
목적 관찰련속혈액정화치료ICU내고납혈증환자적림상료효.방법 96례ICU내고납혈증환자안조치료방식불동분위대조조여치료조각48례.대조조채용상규보수치료,치료조우대조조치료기출상채용련속혈액정화치료.관찰량조환자치료전후혈납농도、기항、뇨소담、혈장삼투압、심솔、평균동맥압변화,예후.결과 치료후,량조환자혈납농도、기항、뇨소담、혈장삼투압교치료전균명현하강,단치료조하강경현저(P＜0.05);량조환자평균동맥압교치료전균명현승고,단치료조승고경현저(P＜0.05).수방1년,치료조분별치유급존활22례(45.83％)、43례(89.58％),명현고우대조조적13례(27.08％)、31례(64.58％),차이유통계학의의(x2=6.75,8.96;P＜ 0.05).결론 림상채용련속혈액정화치료ICU내고납환자,가현저강저기혈납농도,병유효개선기신공능급혈장삼투압,축보은정기생명체정,제고림상료효,종이개선예후.
Objective To observe the clinical effect of continuous blood purification in the treatment of patients with hypernatronemia in ICU.Methods 96 patients with hypernatronemia in ICU were divided into control group and treatment group,48 cases in each group.Control group was treated with conventional conservative treatment,and treatment group was treated with continuous blood purification on the basis of control group.Observed blood sodium concentration,creatinine,urea nitrogen,plasma osmotic pressure,heart rate,mean arterial pressure before and after treatment,prognosis of two groups.Results After treatment,serum sodium concentration,creatinine,urea nitrogen,plasma osmotic pressure of two groups decreased,and those of treatment group decreased more significantly (P＜0.05);mean arterial pressure of two groups increased,and that of treatment group increased more significantly (P＜0.05).The cure rate and the survival rate of treatment group were 45.83％,89.58％ respectively,significantly higher than 27.08％,64.58％ of control group,with statistically significant differences (P＜0.05).Conclusions Continuous blood purification in the treatment of patients with hypematronemia in ICU can significantly decrease serum sodium concentration of patients,and effectively improve renal function and plasma osmotic pressure,gradually stabilize vital signs,improve the clinical efficacy,so as to improve the prognosis.
