国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
International Medicine and Health Guidance News
2015年
22期
3331-3334
,共4页
莫西沙星注射液%左氧氟沙星注射液%下呼吸道感染
莫西沙星註射液%左氧氟沙星註射液%下呼吸道感染
막서사성주사액%좌양불사성주사액%하호흡도감염
Moxifloxacin%Levofloxacin%Lower respiratory infection
目的 观察莫西沙星注射液治疗下呼吸道感染的临床疗效及安全性.方法 将103例下呼吸道感染患者采用随机数字表法分为观察组52例和对照组51例,对照组患者给以左氧氟沙星注射液5 g溶入5％葡萄糖100 ml静脉滴注,1次/d,观察组以莫西沙星注射液静滴给药4g/次,1次/d,两组给药疗程为5～ 14d,评估临床疗效及不良反应.结果 观察组总有效率为92.30％,细菌清除率为95.12％,明显高于对照组的74.50％和76.19％,组间比较差异有统计学意义(x2=4.697、4.579,P＜0.05).观察组总治疗时间为(7.06±2.13)d,明显短于对照组(9.10±1.89)d,差异有统计学意义(t=5.137,P＜0.05).结论 莫西沙星注射液治疗下呼吸道感染疗效确切,且具有良好的安全性.
目的 觀察莫西沙星註射液治療下呼吸道感染的臨床療效及安全性.方法 將103例下呼吸道感染患者採用隨機數字錶法分為觀察組52例和對照組51例,對照組患者給以左氧氟沙星註射液5 g溶入5％葡萄糖100 ml靜脈滴註,1次/d,觀察組以莫西沙星註射液靜滴給藥4g/次,1次/d,兩組給藥療程為5～ 14d,評估臨床療效及不良反應.結果 觀察組總有效率為92.30％,細菌清除率為95.12％,明顯高于對照組的74.50％和76.19％,組間比較差異有統計學意義(x2=4.697、4.579,P＜0.05).觀察組總治療時間為(7.06±2.13)d,明顯短于對照組(9.10±1.89)d,差異有統計學意義(t=5.137,P＜0.05).結論 莫西沙星註射液治療下呼吸道感染療效確切,且具有良好的安全性.
목적 관찰막서사성주사액치료하호흡도감염적림상료효급안전성.방법 장103례하호흡도감염환자채용수궤수자표법분위관찰조52례화대조조51례,대조조환자급이좌양불사성주사액5 g용입5％포도당100 ml정맥적주,1차/d,관찰조이막서사성주사액정적급약4g/차,1차/d,량조급약료정위5～ 14d,평고림상료효급불량반응.결과 관찰조총유효솔위92.30％,세균청제솔위95.12％,명현고우대조조적74.50％화76.19％,조간비교차이유통계학의의(x2=4.697、4.579,P＜0.05).관찰조총치료시간위(7.06±2.13)d,명현단우대조조(9.10±1.89)d,차이유통계학의의(t=5.137,P＜0.05).결론 막서사성주사액치료하호흡도감염료효학절,차구유량호적안전성.
Objective To observe therapeutic efficacy and safety ofmoxifloxacin in the treatment of lower respiratory infection.Methods 103 cases of lower respiratory infection were divided into observation group (n=52) and control group (n=51) with the random number table method.Control group was given intravenous drip oflevofloxacin injection 5 g added into 100 ml 5％ glucose injection once a day,while observation group was given intravenous drip of moxifloxacin injection 4 g added into 100 ml 0.9％ physiological saline injection once a day.Treatment course of 2 groups lasted for 5-14 days.The clinical efficacy and adverse reactions were analyzed.Results The total effective rate was 92.30％,and the bacterial clearance rate was 95.12％ in observation group,while those in control group were 74.50％ and 76.19％,with statistically significant differences between two groups (x 2=4.697,4.579;P＜0.05).The treatment time of observation group was (7.06±2.13)d,significantly shorter than (9.10± 1.89)d of control group,with statistically significant difference between two groups (t=5.137,P＜0.05).Conclusion Moxifloxacin injection in the treatment of lower respiratory infection has curative effect and safety.
