CAJ | 학술논문

目的：研究肝动脉化疗栓塞术配合放射性碘植入治疗肝癌预后因素。方法：收集接受肝动脉化疗栓塞术配合放射性碘治疗的肝癌患者120例，进行 Log-rank 单因素分析分析影响肝癌患者治疗预后的影响因素，多因素 Cox 回归分析分析影响预后的独立风险因素。采用 Kaplan-Meier 生存曲线分析患者的生存情况。结果：120例中位生存期23个月，平均26个月。1年、3年和5年生存率分别为46.3%、59.8%和36.2%。其中 TNM 分期、Child-Pugh 分级、血清 AFP 与肝癌肝动脉化疗栓塞术配合放射性碘植入治疗的预后具有相关性。结论：TNM 分期、Child-Pugh 分级、血清 AFP 含量是肝动脉化疗栓塞术配合放射性碘植入治疗肝癌预后的影响因素。
목적：연구간동맥화료전새술배합방사성전식입치료간암예후인소。방법：수집접수간동맥화료전새술배합방사성전치료적간암환자120례，진행 Log-rank 단인소분석분석영향간암환자치료예후적영향인소，다인소 Cox 회귀분석분석영향예후적독립풍험인소。채용 Kaplan-Meier 생존곡선분석환자적생존정황。결과：120례중위생존기23개월，평균26개월。1년、3년화5년생존솔분별위46.3%、59.8%화36.2%。기중 TNM 분기、Child-Pugh 분급、혈청 AFP 여간암간동맥화료전새술배합방사성전식입치료적예후구유상관성。결론：TNM 분기、Child-Pugh 분급、혈청 AFP 함량시간동맥화료전새술배합방사성전식입치료간암예후적영향인소。
Objective:To identify the prognostic factor Transcatheter arterial chemoembolization com-bined radioactive iodine implantation for treatment Hepatocellular carcinoma.Methods:One hundred and twenty pa-tients who underwent transcatheter arterial chemoembolization combined radioactive iodine implantation for treat-ment Hepatocellular carcinoma were evaluated between 201 1 and2014.Univariableand multivariable Cox regression analysis was performed to assess the factors associated with patient survival.The cumulative survival curves were created using the Kaplan-Meier method.Results:The median survival time was 23 months and the average survival time was 26 months.The survival rates were 46.3% at one year,59.8% at three year,and 12% at five years.In the multivariable Cox regression analysis,TNM stage,Child-Pugh class and serum AFP level were significant fac-tors associated with patient survival.Conclusion:TNM stage,Child-Pugh class and serum AFP level are the prog-nostic factors of transcatheter arterial chemoembolization combined radioactive iodine implantation for treatment Hepatocellular carcinoma.