CAJ | 학술논문

目的:探究2型糖尿病患者接受甘精胰岛素联合瑞格列奈进行治疗的临床效果.方法:纳入本院近年来收治2型糖尿病患者为本次研究对象,随机抽取80例并根据治疗方案差异将其分为对照组与观察组.对照组患者40例,单纯接受瑞格列奈治疗,观察组患者40例,在对照组治疗基础上联合甘精胰岛素.对比2组患者临床治疗效果及治疗安全性.结果:分别于治疗前后对比2组患者临床指标FPG、2hPBG值、糖化血红蛋白(HbAlC),2组患者治疗后均有所改善,观察组患者改善程度显著优于对照组,差异有统计学意义(P<0.05);观察组患者胰岛素功能改善显著优于对照组,差异有统计学意义(P<0.05);治疗过程中记录对比2组患者药物不良反应发生情况,2组对比并不具有统计学意义(P>0.05).结论:对2型糖尿病患者应用甘精胰岛素联合瑞格列奈进行治疗,相对于以往常规治疗方案其疗效有显著提升,且不会增加药物相关不良反应,保障疗程顺利进行以及患者身体健康,值得临床普及推广.
목적:탐구2형당뇨병환자접수감정이도소연합서격렬내진행치료적림상효과.방법:납입본원근년래수치2형당뇨병환자위본차연구대상,수궤추취80례병근거치료방안차이장기분위대조조여관찰조.대조조환자40례,단순접수서격렬내치료,관찰조환자40례,재대조조치료기출상연합감정이도소.대비2조환자림상치료효과급치료안전성.결과:분별우치료전후대비2조환자림상지표FPG、2hPBG치、당화혈홍단백(HbAlC),2조환자치료후균유소개선,관찰조환자개선정도현저우우대조조,차이유통계학의의(P<0.05);관찰조환자이도소공능개선현저우우대조조,차이유통계학의의(P<0.05);치료과정중기록대비2조환자약물불량반응발생정황,2조대비병불구유통계학의의(P>0.05).결론:대2형당뇨병환자응용감정이도소연합서격렬내진행치료,상대우이왕상규치료방안기료효유현저제승,차불회증가약물상관불량반응,보장료정순리진행이급환자신체건강,치득림상보급추엄.
Objective:To explore the patients with type 2 diabetes insulin glargine combined with repaglinide in the treatment of the clinical effect. Methods: 2 patients with type 80 diabetes were treated in our hospital in recent years. The patients were randomly selected and divided into control group and observation group. The control group of 40 patients, simply accept repaglinide treatment, the observation group of 40 patients in the control group were treated with insulin glargine. To compare the clinical efficacy and safety of the 2 groups.Results: FPG, 2hPBG, glycosylated hemoglobin (HbAlC) were compared between 2 groups, and the improvement of patients in the 2 groups were significantly better than those in the control group, the difference was statistically significant (P < 0.05). The difference was statistically significant (P < 0.05). The difference between the 2 groups was not statistically significant (P > 0.05). Conclusion:for patients with type 2 diabetes Gan insulin glargine combined with repaglinide treatment, significantly improved compared with the conventional treatment, its efficacy, and does not increase the adverse drug reactions, security course smoothly and the patient is healthy, worthy of clinical popularization.