CAJ | 학술논문

目的描述中国慢性病前瞻性研究(CKB)10个地区人群肺功能指标水平和气流受限现患率的地区差异.方法剔除基线调查时肺功能指标异常个体后,分析10个地区512 495名30～79岁调查对象肺功能指标水平(FEV1和FVC)和气流受限(分别采用GOLD标准和LLN标准进行判断)现患率的地区差异.结果 10个地区男性的FEV1(2.66 L)和FVC(3.16 L)均高于女性(1.99 L和2.35 L);河南和哈尔滨人群FEV1和FVC高于其他地区.基于GOLD标准的气流受限现患率:男性(5.13％)高于女性(3.75％);农村人群高于城市(男性:6.32％%vs.3.47％;女性:4.26％vs.2.97％);四川人群现患率最高(男性为13.34％,女性为10.70％),其次是苏州、河南和湖南.基于LLN标准的气流受限现患率(男性为6.93％,女性为6.29％)略高于GOLD标准,但地区差异近似.结论 CKB的10个地区人群无论在肺功能指标水平和气流受限现患率上均存在明显的地区差异.
목적 묘술중국만성병전첨성연구(CKB)10개지구인군폐공능지표수평화기류수한현환솔적지구차이.방법 척제기선조사시폐공능지표이상개체후,분석10개지구512 495명30～79세조사대상폐공능지표수평(FEV1화FVC)화기류수한(분별채용GOLD표준화LLN표준진행판단)현환솔적지구차이.결과 10개지구남성적FEV1(2.66 L)화FVC(3.16 L)균고우녀성(1.99 L화2.35 L);하남화합이빈인군FEV1화FVC고우기타지구.기우GOLD표준적기류수한현환솔:남성(5.13％)고우녀성(3.75％);농촌인군고우성시(남성:6.32％%vs.3.47％;녀성:4.26％vs.2.97％);사천인군현환솔최고(남성위13.34％,녀성위10.70％),기차시소주、하남화호남.기우LLN표준적기류수한현환솔(남성위6.93％,녀성위6.29％)략고우GOLD표준,단지구차이근사.결론 CKB적10개지구인군무론재폐공능지표수평화기류수한현환솔상균존재명현적지구차이.
Objective To describe the area specific differences in lung function indices and prevalence of airflow obstruction (AFO) in adults found by China Kadoorie Biobank (CKB) study, involving 512 495 adults, in 10 areas in China.Methods The detailed information on lung function indices (FEV, and FVC) and prevalence of AFO (diagnosed according to GOLD and LLN criteria) of subjects aged 30-79 years were analyzed, those with abnormal lung function indices at baseline survey were excluded.Results The FEV1 and FVC among males (2.66 L, 3.16 L) were higher than those among females (1.99 L, 2.35 L).The FEV1 and FVC were highest in Henan and Harbin.The prevalence of AFO diaonosed according to GOLD criteria was 5.13％ in males, higher than that in females (3.75％).The prevalence of AFO was higher in rural area than in urban area (males: 6.32％vs.3.47％;females: 4.26％ vs.2.97％).The prevalence of AFO was highest in Sichuan (13.34％ in males, 10.70％ in females), followed by that in Suzhou, Henan and Hunan.The prevalence of AFO diagnosed according to LLN criteria (6.93％ in males, 6.29％ in females) was higher than that diagnosed according to GOLD criteria, but the area specific difference was similar.Conclusion The lung function indices and the prevalence of AFO in adults varied greatly among the 10 areas covered by CKB study.