CAJ | 학술논문

目的了解河南省2012-2014年新报告HIV感染者中HCV抗体的流行情况.方法通过艾滋病综合防治数据信息管理系统对河南省2012年7月1日至2014年6月30日新报告的HIV感染者进行信息整理、HIV-1 BED新发感染检测和HCV抗体检测.结果 4 267例新报告HIV感染者中HCV抗体阳性率为13.19％(563/4 267),感染途径为注射吸毒者的HCV抗体阳性率最高(77.27％),采血浆/输血、异性性传播、同性性传播和母婴传播人群的HCV抗体阳性率分别为15.06％、15.81％、3.74％和8.96％.开封(32.04％)、驻马店(25.00％)、商丘(25.00％)、周口(18.86％)和南阳(14.67％)为HCV抗体阳性率最高的前五个省辖市.BED阳性者(HIV新近感染者)中HCV抗体阳性率为7.50％(86/1 146).多因素logistic回归分析发现:BED阴性、年龄＞40岁、农民、HIV感染途径为注射吸毒以及报告地区为开封市、南阳市、商丘市、驻马店市和周口市为HCV感染的危险因素.结论 2012-2014年河南省新报告HIV感染者中HCV抗体流行率有降低的趋势,但是部分地区和重点人群仍存在较高的HCV抗体流行率.
목적 료해하남성2012-2014년신보고HIV감염자중HCV항체적류행정황.방법 통과애자병종합방치수거신식관리계통대하남성2012년7월1일지2014년6월30일신보고적HIV감염자진행신식정리、HIV-1 BED신발감염검측화HCV항체검측.결과 4 267례신보고HIV감염자중HCV항체양성솔위13.19％(563/4 267),감염도경위주사흡독자적HCV항체양성솔최고(77.27％),채혈장/수혈、이성성전파、동성성전파화모영전파인군적HCV항체양성솔분별위15.06％、15.81％、3.74％화8.96％.개봉(32.04％)、주마점(25.00％)、상구(25.00％)、주구(18.86％)화남양(14.67％)위HCV항체양성솔최고적전오개성할시.BED양성자(HIV신근감염자)중HCV항체양성솔위7.50％(86/1 146).다인소logistic회귀분석발현:BED음성、년령＞40세、농민、HIV감염도경위주사흡독이급보고지구위개봉시、남양시、상구시、주마점시화주구시위HCV감염적위험인소.결론 2012-2014년하남성신보고HIV감염자중HCV항체류행솔유강저적추세,단시부분지구화중점인군잉존재교고적HCV항체류행솔.
Objective To study the prevalence of antibody to hepatitis C virus (anti-HCV) among newly reported HIV infection cases in Henan province, 2012-2014.Methods HIV-1 BED incidence test and anti-HCV test were conducted in newly diagnosed HIV infection cases in Henan,which were reported through national AIDS information system between 1 July 2012 and 30 June 2014.Results The data of 4 267 newly reported HIV-1 infection cases were analyzed, the positive rate of anti-HCV was 13.19％ (563/4 267).The anti HCV was highest in those infected with HIV through injection drug use (77.27％), the anti-HCV positive rates in those infected with HIV through blood donation/transfusion, heterosexual contact, homosexual contact and mother-to-child transmission were 15.06％, 15.81％, 3.74％ and 8.96％, respectively.Kaifeng (32.04％), Nanyang (14.67％), Shangqiu (25.00％), Zhumadian (25.00％) and Zhoukou (18.86％) were the first five prefectures with the high anti-HCV positive rates.The anti-HCV positive rate in BED positive patients (recent HIV-1 infections) was 7.50％ (86/1 146).The multivariate logistic regressions analysis revealed that BED negative, aged ＞40 years, being farmer, HIV infection though injection drug use and living in in Kaifeng, Nanyang, Shangqiu, Zhumadian and Zhoukou were the risk factors for HCV infection.Conclusion The positive rate of anti-HCV declined between 2012-2014 in newly reported HIV infection cases in Henan, but the positive rate of anti-HCV was high in risk population and in some areas.