中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2015年
42期
3407-3410
,共4页
睡眠呼吸暂停,阻塞性%问卷调查%多导睡眠描记术%筛查
睡眠呼吸暫停,阻塞性%問捲調查%多導睡眠描記術%篩查
수면호흡잠정,조새성%문권조사%다도수면묘기술%사사
Sleep apnea,obstructive%Questionnaires%Polysomnography%Screening
目的 评估Berlin问卷、STOP问卷、STOP-Bang(SBQ)问卷和Epworth嗜睡量表(ESS)在阻塞性睡眠呼吸暂停综合征(OSA)患者筛查中的应用价值.方法 对2011年9月至2012年5月四川大学华西医院睡眠医学中心连续就诊的可疑350例OSA患者[男302例,女48例;年龄19 ~68岁,平均(42.9±11.0)岁]进行整夜多导睡眠图(PSG)记录,并填写Berlin问卷、STOP问卷、SBQ问卷和ESS评分.依据呼吸暂停低通气指数(AHI)将患者分为单纯鼾症组(<5次/h)、轻度OSA组(5~<15次/h)、中度OSA组(15~ <30次/h)、重度OSA组(≥30次/h).计算每个量表的敏感度、特异度、阳性预测值、阴性预测值,绘制受试者工作特征(ROC)曲线,分析4种量表评分预测OSA的准确性.结果 在判断轻-中-重(AHI≥5次/h)、中-重(AHI≥15次/h)、重度(AHI≥30次/h)OSA时,SBQ问卷的敏感度均最高(分别为94%、94%、95%),Berlin问卷ROC曲线下面积最大(分别为0.784、0.732、0.771),ESS敏感度最差(分别为43%、45%、48%).结论 同PSG比较,SBQ问卷诊断OSA的敏感度最高,特异性较差;Berlin问卷可能有更高的准确性.
目的 評估Berlin問捲、STOP問捲、STOP-Bang(SBQ)問捲和Epworth嗜睡量錶(ESS)在阻塞性睡眠呼吸暫停綜閤徵(OSA)患者篩查中的應用價值.方法 對2011年9月至2012年5月四川大學華西醫院睡眠醫學中心連續就診的可疑350例OSA患者[男302例,女48例;年齡19 ~68歲,平均(42.9±11.0)歲]進行整夜多導睡眠圖(PSG)記錄,併填寫Berlin問捲、STOP問捲、SBQ問捲和ESS評分.依據呼吸暫停低通氣指數(AHI)將患者分為單純鼾癥組(<5次/h)、輕度OSA組(5~<15次/h)、中度OSA組(15~ <30次/h)、重度OSA組(≥30次/h).計算每箇量錶的敏感度、特異度、暘性預測值、陰性預測值,繪製受試者工作特徵(ROC)麯線,分析4種量錶評分預測OSA的準確性.結果 在判斷輕-中-重(AHI≥5次/h)、中-重(AHI≥15次/h)、重度(AHI≥30次/h)OSA時,SBQ問捲的敏感度均最高(分彆為94%、94%、95%),Berlin問捲ROC麯線下麵積最大(分彆為0.784、0.732、0.771),ESS敏感度最差(分彆為43%、45%、48%).結論 同PSG比較,SBQ問捲診斷OSA的敏感度最高,特異性較差;Berlin問捲可能有更高的準確性.
목적 평고Berlin문권、STOP문권、STOP-Bang(SBQ)문권화Epworth기수량표(ESS)재조새성수면호흡잠정종합정(OSA)환자사사중적응용개치.방법 대2011년9월지2012년5월사천대학화서의원수면의학중심련속취진적가의350례OSA환자[남302례,녀48례;년령19 ~68세,평균(42.9±11.0)세]진행정야다도수면도(PSG)기록,병전사Berlin문권、STOP문권、SBQ문권화ESS평분.의거호흡잠정저통기지수(AHI)장환자분위단순한증조(<5차/h)、경도OSA조(5~<15차/h)、중도OSA조(15~ <30차/h)、중도OSA조(≥30차/h).계산매개량표적민감도、특이도、양성예측치、음성예측치,회제수시자공작특정(ROC)곡선,분석4충량표평분예측OSA적준학성.결과 재판단경-중-중(AHI≥5차/h)、중-중(AHI≥15차/h)、중도(AHI≥30차/h)OSA시,SBQ문권적민감도균최고(분별위94%、94%、95%),Berlin문권ROC곡선하면적최대(분별위0.784、0.732、0.771),ESS민감도최차(분별위43%、45%、48%).결론 동PSG비교,SBQ문권진단OSA적민감도최고,특이성교차;Berlin문권가능유경고적준학성.
Objective To evaluate the clinical utility of four questionnaires of Berlin,STOP,STOP-Bang (SBQ) and Epworth Sleepiness Scale (ESS) in the screening of patients with obstructive sleep apnea (OSA).Methods A total of 350 consecutive patients (302 males and 48 females,19-86 years old,average (42.9 ± 11.0) years old) with suspected OSA who underwent an overnight polysomnography (PSG) were recruited into this study.Four questionnaires of Berlin,STOP,SBQ and ESS were completed.Based on the severity of OSA which was determined by apnea-hypopnea index (AHI),the patients were classified into four groups of primary snoring (<5 events/h),mild (5-< 15 events/h),moderate (15-< 30 events/h) and severe OSA (≥ 30 events/h).Sensitivity,specificity,positive predictive values,negative predictive values and the area under the receiver operating characteristics curve of four questionnaires were calculated.Results Using mild-moderate-severe (≥5 events/h),moderate-severe (≥ 15 events/h),and severe (≥ 30 events/h) OSA as cutoffs,SBQ had the highest sensitivity (94%,94% and 95%,respectively).Berlin Questionnaire had the largest area under the receiver operating characteristics curve (0.784,0.732,and 0.771,respectively).ESS had the lowest sensitivity (43%,45% and 48%,respectively).Conclusions Compared to the PSG,SBQ questionnaire has the highest sensitivity,but lower specificity;in contrast,Berlin questionnaire may have better accuracy.