CAJ | 학술논문

目的：探讨首次脑梗死患者血清同型半胱氨酸（Hcy）含量与脑梗死发生的关系。方法收集2012年1月至2013年10月首次发病的72例急性脑梗死患者，其中动脉硬化性血栓形成性脑梗死（ ACI）38例，腔隙性脑梗死（LI）24例，脑栓塞（CE）10例，收集同期健康体检者（对照组）50例，测定血清 Hcy 含量。结果 ACI 组、LI 组及 CE 组血清 Hcy含量明显高于对照组（P ＜0.01）；三组间血清 Hcy 含量比较差异未见统计学意义（P ＞0.05）。结论急性脑梗死患者Hcy 含量明显增高。观察 Hcy 水平的改变对于预测脑梗死的发生有意义。
목적：탐토수차뇌경사환자혈청동형반광안산（Hcy）함량여뇌경사발생적관계。방법수집2012년1월지2013년10월수차발병적72례급성뇌경사환자，기중동맥경화성혈전형성성뇌경사（ ACI）38례，강극성뇌경사（LI）24례，뇌전새（CE）10례，수집동기건강체검자（대조조）50례，측정혈청 Hcy 함량。결과 ACI 조、LI 조급 CE 조혈청 Hcy함량명현고우대조조（P ＜0.01）；삼조간혈청 Hcy 함량비교차이미견통계학의의（P ＞0.05）。결론급성뇌경사환자Hcy 함량명현증고。관찰 Hcy 수평적개변대우예측뇌경사적발생유의의。
Objective To investigate the relationship between homocysteine levels and cerebral infarction in cerebral infarc-tion after the first attack. Methods A total of 72 patients with acute cerebral infarction were collected from January 2012 to Oc-tober 2013. Among them,38 cases were atherothrobotic cerebral infarction(ACI),24 cases were lacuna infarction(LI),and 10 cases were cerebral embolism infarction(CE). At the same time,50 healthy subiects were collected as the controls. All of them were measured with the levels of blood homocysteine. Results The levels of blood homocysteine in patients with ACI,LI and CE were significantly higher than that in normal controls(all P < 0. 01). The levels of blood homocysteine had no obvious differ-ence between ACI,LI and CE group(P > 0. 05). Conclusion The blood concentrations of homocysteine in patients with acute cerebral infarction increase significantly. To observe the changes of blood level of homocysteine is very valuable to forecast the oc-currence of cerebral infarction.