CAJ | 학술논문

目的:探讨"健脑安神"针刺法对失眠患者临床疗效和血清TNF-α、IL-6的影响. 方法:选取符合诊断标准的失眠患者36例进行"健脑安神"针刺法治疗,在治疗前后分别检测其匹茨堡睡眠指数积分和血清中TNF-α、 IL-6的含量,每日针刺1次,每周5次,10次为1个疗程. 结果:治疗2个疗程后,36例中痊愈17例,显效10例,有效6例,无效3例,总有效率为91 .67%. 治疗前后TNF-α和IL-6差异均P<00.5 ,表明治疗前后差异有显著意义. 结论:"健脑安神"针刺法可以改善患者睡眠质量、升高失眠患者血清IL -6含量、降低TNF-α含量,提示针刺后患者血清IL-6和TNF -α含量发生变化, 可能是健脑安神针刺法治疗失眠的作用机制之一.
목적:탐토"건뇌안신"침자법대실면환자림상료효화혈청TNF-α、IL-6적영향. 방법:선취부합진단표준적실면환자36례진행"건뇌안신"침자법치료,재치료전후분별검측기필자보수면지수적분화혈청중TNF-α、 IL-6적함량,매일침자1차,매주5차,10차위1개료정. 결과:치료2개료정후,36례중전유17례,현효10례,유효6례,무효3례,총유효솔위91 .67%. 치료전후TNF-α화IL-6차이균P<00.5 ,표명치료전후차이유현저의의. 결론:"건뇌안신"침자법가이개선환자수면질량、승고실면환자혈청IL -6함량、강저TNF-α함량,제시침자후환자혈청IL-6화TNF -α함량발생변화, 가능시건뇌안신침자법치료실면적작용궤제지일.
Objective:To observe the effect of acupuncture therapy of strengthening brain and calming mind on clinical efficacy and serum TNF -αand IL-6 in patients with insomnia .Meth ods:36 cases definitely diagnosed with insomnia were treated by the acupuncture therapy of strengthening brain and calming mind ,and Pittsburgh Sleep Index Point was detected and TNF -αand IL-6 content in serum were measured before and after treat-ment .Do acupuncture treatment once a day ,5 times a week ,10 times as a course of treatment .Results:After two courses of treatment ,17 recovered;10 had a significant effect;6 were effective;3 were ineffectiven in 36 cases, and the total efficiency was 91 .67%.Before and after treatment ,mean TNF-αand IL-6 difference , statisti-cally, both P<0.05, indicating a significant difference before and after treatment .Conclusion:The acupunc-ture therapy of strengthening brain and calming mind is effective for treating insomnia ,and it can increase IL-6 levels and lower TNF-αlevels,indicating that the acupuncture therapy plays a role in TNF -αand IL-6 levels,which may be one of the mechanisms for treating insomnia .