CAJ | 학술논문

目的：分析耐多药肺结核患者合并肺部真菌感染的原因。方法运用回顾性调查法分析2011年2月至2015年3月入住我院确诊为耐多药肺结核患者合并肺部真菌感染的62例患者的病例资料。结果长期使用糖皮质激素和广谱强效抗生素及伴随糖尿病是导致耐多药肺结核合并肺部真菌感染的主要因素。病菌感染以白色念珠菌为主。结论耐多药肺结核患者免疫功能低是真菌感染的基础，长期反复使用广谱抗生素和糖皮质激素是真菌感染的条件。耐多药肺结核患者极易感染肺部真菌，因此，提高对耐多药肺结核合并真菌感染的认识，有助于控制继发真菌感染，提高临床疗效。
목적：분석내다약폐결핵환자합병폐부진균감염적원인。방법운용회고성조사법분석2011년2월지2015년3월입주아원학진위내다약폐결핵환자합병폐부진균감염적62례환자적병례자료。결과장기사용당피질격소화엄보강효항생소급반수당뇨병시도치내다약폐결핵합병폐부진균감염적주요인소。병균감염이백색념주균위주。결론내다약폐결핵환자면역공능저시진균감염적기출，장기반복사용엄보항생소화당피질격소시진균감염적조건。내다약폐결핵환자겁역감염폐부진균，인차，제고대내다약폐결핵합병진균감염적인식，유조우공제계발진균감염，제고림상료효。
Objective To analyze the factors of multidrug resistance pulmonary tuberculosis complicated with fugal infection.Methods From February 2011 to March 2015, 62 patients of multidrug resistance pulmonary tuberculosis complicated with fugal infection in our hospital who accepted treatment were selected as the study samples and al the case data using retrospectively analyzed.Results Long-term use of glucocorticoid and broad-spectrum potent antibiotics, and patients of multidrug resistance tuberculosis accompanied by diabetes were the main factor of pulmonary fungus infection.Bacterial infection was given priority to with candida albicans. Conclusion Low immune function of patients with multi-drug resistant pulmonary tuberculosis is the basis of fungal infection, long-term repeated use of broad-spectrum antibiotics and glucocorticoid is a fungal infection. It is common that fugal infection occurred in multidrug resistance tuberculosis cases. Therefore, improving the recognition about multidrug resistance tuberculosis complicated with fugal infection will be contribute to control fugal infection and enhance clinical effacy.