中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
11期
1437-1438,1439
,共3页
甲状腺切除术%异丙酚%芬太尼%血流动力学%清醒时间
甲狀腺切除術%異丙酚%芬太尼%血流動力學%清醒時間
갑상선절제술%이병분%분태니%혈류동역학%청성시간
Thyroidectomy%Propofol%Fentanyl%Hemodynamics%Period of awakening
目的：探讨静脉泵注异丙酚及芬太尼间断推注麻醉对甲状腺切除患者血流动力学的影响。方法：选取2012年11月—2014年11月行甲状腺切除手术的患者92例作为研究对象，按随机数字表法将患者分对照组和观察组各46例，对照组患者行双侧颈前丛神经阻滞麻醉，观察组患者行静脉泵注异丙酚及芬太尼间断推注麻醉，观察2组患者的血流动力学变化情况，并记录2组患者的苏醒期躁动及咳嗽的发生情况。结果：观察组患者的血流动力学稳定性显著优于对照组，差异有统计学意义（P＜0.05）；观察组苏醒期躁动、咳嗽的发生率为10.87％（5／46）、4.35％（2／46），均显著低于对照组的28.26％（13／46）、17.39％（8／46），差异均有统计学意义（P＜0.05）。结论：静脉泵注异丙酚及芬太尼间断推注麻醉可减少对甲状腺切除术患者血流动力学的影响，提高手术安全性，值得临床推广。
目的：探討靜脈泵註異丙酚及芬太尼間斷推註痳醉對甲狀腺切除患者血流動力學的影響。方法：選取2012年11月—2014年11月行甲狀腺切除手術的患者92例作為研究對象，按隨機數字錶法將患者分對照組和觀察組各46例，對照組患者行雙側頸前叢神經阻滯痳醉，觀察組患者行靜脈泵註異丙酚及芬太尼間斷推註痳醉，觀察2組患者的血流動力學變化情況，併記錄2組患者的囌醒期躁動及咳嗽的髮生情況。結果：觀察組患者的血流動力學穩定性顯著優于對照組，差異有統計學意義（P＜0.05）；觀察組囌醒期躁動、咳嗽的髮生率為10.87％（5／46）、4.35％（2／46），均顯著低于對照組的28.26％（13／46）、17.39％（8／46），差異均有統計學意義（P＜0.05）。結論：靜脈泵註異丙酚及芬太尼間斷推註痳醉可減少對甲狀腺切除術患者血流動力學的影響，提高手術安全性，值得臨床推廣。
목적：탐토정맥빙주이병분급분태니간단추주마취대갑상선절제환자혈류동역학적영향。방법：선취2012년11월—2014년11월행갑상선절제수술적환자92례작위연구대상，안수궤수자표법장환자분대조조화관찰조각46례，대조조환자행쌍측경전총신경조체마취，관찰조환자행정맥빙주이병분급분태니간단추주마취，관찰2조환자적혈류동역학변화정황，병기록2조환자적소성기조동급해수적발생정황。결과：관찰조환자적혈류동역학은정성현저우우대조조，차이유통계학의의（P＜0.05）；관찰조소성기조동、해수적발생솔위10.87％（5／46）、4.35％（2／46），균현저저우대조조적28.26％（13／46）、17.39％（8／46），차이균유통계학의의（P＜0.05）。결론：정맥빙주이병분급분태니간단추주마취가감소대갑상선절제술환자혈류동역학적영향，제고수술안전성，치득림상추엄。
OBJECTIVE:To explore the effects of intravenous-infusion of propofol and discontinuous intravenous-infusion anesthesia of fentanyl on hemodynamics of patients undergoing thyroidectomy . METHODS: 92 patients undergoing thyroidectomy admitted into the hospital from Nov .2011 to Nov.2014 were selected as the research objects.According to the mode of anesthesia , the patients were divided into control group and observation group .46 patients in control group received bilateral anterior cervical plexus block anesthesia while the other 46 patients in observation group received intravenous infusion anesthesia of propofol and fentanyl .The changes of hemodynamics in two group of patients were observed .The occurrence probabilities of restlessness and cough in two group of patients during the period of awakening were recorded .RESULTS: The hemodynamic stability of the observation group was significantly better than that in the control group , the difference was statistically significant ( P <0.05 ) . The occurrence probabilities of restlessness and cough in the observation group were [ 10.87%( 5/46 ) ] and [ 4.35%(2/46)], which were significantly lower than that in the control group [28.26%(13/46)]and [17.39%(8/46)], the difference was statistically significant ( P <0.05 ) . CONCLUSIONS: Intravenous-infusion of propofol and discontinuous intravenous-infusion anesthesia of fentanyl can reduce the effects on hemodynamics of patients undergoing thyroidectomy , improve the security of operation .It is worthy of clinical promotion .
