CAJ | 학술논문

目的：探究肠易激综合征患者在常规治疗基础上联合小剂量氟西汀治疗的临床效果及推广价值。方法纳入本院近年来收治肠易激综合征患者为本次研究对象，随机抽取100例并根据治疗方案差异将其分为对照组与观察组。对照组患者50例，接受常规方案治疗，观察组患者50例，在常规治疗基础上联合小剂量氟西汀。对比2组患者临床治疗效果及不良反应发生情况。结果完成治疗后对2组患者临床疗效进行评估，观察组患者临床治疗总有效率为96.0%，对照组患者治疗总有效率为76.0%，两者对比差异有统计学意义（P＜0.05）；观察组患者不良反应出现概率相对于对照组差异无统计学意义（P>0.05）。结论对肠易激综合征患者除了进行常规治疗，还可以联合小剂量氟西汀，不但能明显提升临床治疗效果且可不会提升患者相关药物不良反应，值得临床普及推广。
목적：탐구장역격종합정환자재상규치료기출상연합소제량불서정치료적림상효과급추엄개치。방법납입본원근년래수치장역격종합정환자위본차연구대상，수궤추취100례병근거치료방안차이장기분위대조조여관찰조。대조조환자50례，접수상규방안치료，관찰조환자50례，재상규치료기출상연합소제량불서정。대비2조환자림상치료효과급불량반응발생정황。결과완성치료후대2조환자림상료효진행평고，관찰조환자림상치료총유효솔위96.0%，대조조환자치료총유효솔위76.0%，량자대비차이유통계학의의（P＜0.05）；관찰조환자불량반응출현개솔상대우대조조차이무통계학의의（P>0.05）。결론대장역격종합정환자제료진행상규치료，환가이연합소제량불서정，불단능명현제승림상치료효과차가불회제승환자상관약물불량반응，치득림상보급추엄。
Objective: To explore the clinical effect and popularization value of small dose fiuoxetine combined with small dose of fiuoxetine in the treatment of irritable bowel syndrome.Methods: 100 patients with irritable bowel syndrome were treated in our hospital in recent years. The patients were randomly selected and divided into control group and observation group. In the control group, 50 patients were treated with conventional therapy, and 50 patients were treated with low dose of fiuoxetine on the basis of conventional therapy. The clinical effect and adverse reactions of the 2 groups were compared.Results: after treatment, the clinical efficacy of the 2 groups were evaluated, the total effective rate was 96% in the observation group, the total effective rate was 76% in the control group, the difference was statistically significant (P<0.05).Conclusion: in addition to conventional therapy, patients with irritable bowel syndrome can also be combined with small dose of fiuoxetine, not only can significantly improve the clinical treatment effect and can not improve the patients related adverse drug reactions, it is worthy of clinical popularization and promotion.