医学信息
醫學信息
의학신식
Medical Information
2015年
44期
303-303
,共1页
长期饮酒%亚急性联合变性%分析
長期飲酒%亞急性聯閤變性%分析
장기음주%아급성연합변성%분석
Chronic alcohol consumption%Subacute combined degeneration%VitB12%Treatment
目的总结长期饮酒所致脊髓亚急性联合变性（SCD）临床特点、诊断、鉴别诊断及治疗。方法对10例临床确诊的SCD患者的临床资料进行回顾性分析。结果60%的SCD患者有大细胞贫血，70%有血清VitB12水平下降，40%有叶酸偏低，脊髓MRI检查发现20%的患者有脊髓后索特异性异常信号，30%的患者肌电图有异常改变，经VitB12治疗后（部分患者合用叶酸），80%患者的临床症状基本消失。结论长期饮酒所致SCD，只要早期诊断、早期治疗，疗效良好；检测患者的VitB12水平有确诊意义；肌电图、脊髓MRI等检查可铺助诊断。
目的總結長期飲酒所緻脊髓亞急性聯閤變性（SCD）臨床特點、診斷、鑒彆診斷及治療。方法對10例臨床確診的SCD患者的臨床資料進行迴顧性分析。結果60%的SCD患者有大細胞貧血，70%有血清VitB12水平下降，40%有葉痠偏低，脊髓MRI檢查髮現20%的患者有脊髓後索特異性異常信號，30%的患者肌電圖有異常改變，經VitB12治療後（部分患者閤用葉痠），80%患者的臨床癥狀基本消失。結論長期飲酒所緻SCD，隻要早期診斷、早期治療，療效良好；檢測患者的VitB12水平有確診意義；肌電圖、脊髓MRI等檢查可鋪助診斷。
목적총결장기음주소치척수아급성연합변성（SCD）림상특점、진단、감별진단급치료。방법대10례림상학진적SCD환자적림상자료진행회고성분석。결과60%적SCD환자유대세포빈혈，70%유혈청VitB12수평하강，40%유협산편저，척수MRI검사발현20%적환자유척수후색특이성이상신호，30%적환자기전도유이상개변，경VitB12치료후（부분환자합용협산），80%환자적림상증상기본소실。결론장기음주소치SCD，지요조기진단、조기치료，료효량호；검측환자적VitB12수평유학진의의；기전도、척수MRI등검사가포조진단。
Objective To sum up the clinical features, diagnosis, dif erential diagnosis and treatment of spinal subacute combined degeneration (SCD) caused by chronic alcohol consumption. Methods Clinical data of 10 patients with SCD were retrospectively analyzed. Results 60% of SCD in patients with large cel anemia, 70% had decreased serum vitamin B12 levels, 40% of folic acid is low, spinal cord MRI examination found that 20% of the patients had spinal cord after Sauter specific abnormal signal, 30% of the patients with EMG is abnormal, the VitB12 treatment (some patients combined with folic acid), 80%of patients with clinical symptoms disappeared. Conclusion The long-term alcohol consumption SCD, as long as the early diagnosis, early treatment, the ef ect is good, the VitB12 level of patients with diagnosis of the significance of the diagnosis, EMG, spinal cord MRI and other examination can help diagnose.
