针灸临床杂志
針灸臨床雜誌
침구림상잡지
Journal of Clinical Acupuncture and Moxibustion
2015年
11期
45-48
,共4页
新生儿%缺血缺氧性脑病%单唾液酸四己糖神经节苷脂钠%电针%穴位注射
新生兒%缺血缺氧性腦病%單唾液痠四己糖神經節苷脂鈉%電針%穴位註射
신생인%결혈결양성뇌병%단타액산사기당신경절감지납%전침%혈위주사
New birth%Neonatal hypoxic ischemic encephalopathy%Single saliva acid four ganglioside sodium%Electroacupuncture%Acupoint injection
目的:研究电针联合穴位注射单唾液酸四己糖神经节苷脂钠治疗新生儿缺血缺氧性脑病的临床疗效及机制,为此类疾病提供新的综合治疗方案.方法:选取2014 年3月~2015 年3 月本院收治的166例缺血缺氧性脑病新生患儿,按出生先后顺序随机分治疗组、观察组,治疗组每日吸氧及静脉滴注胞二磷胆碱、能量等对症治疗,观察组在此治疗基础上头针及体针电针刺激20 min,并取"四神通、百会、足三里"穴位注射单唾液酸四己糖神经节苷脂钠.动态观察治疗前、7天、14天、21天脑电图( EEG )病理性棘波振幅、局部脑血流量( rCBF );测定血浆( CK-BB );采用新生儿20 项神经行为评分办法( NBNA)评分并统计总有效率.结果:观察组于第7天、14天、21天 CK-BB及EEG明显降低、NBNA及rCBF显著提高(F=33.579,P<0.05),总有效率达97.59%,与治疗组比较P<0.05,差异均有统计学意义.结论:通过对缺血缺氧性脑病新生儿头针、体针电针刺激可疏通经络、激发患儿经气,松弛新生儿局部脑缺血区血管平滑肌以改善脑缺血区微循环而达到增加脑血流量的目的,穴位注射单唾液酸四己糖神经节苷脂钠可营养脑组织及修复受损神经纤维而促进脑功能的恢复.
目的:研究電針聯閤穴位註射單唾液痠四己糖神經節苷脂鈉治療新生兒缺血缺氧性腦病的臨床療效及機製,為此類疾病提供新的綜閤治療方案.方法:選取2014 年3月~2015 年3 月本院收治的166例缺血缺氧性腦病新生患兒,按齣生先後順序隨機分治療組、觀察組,治療組每日吸氧及靜脈滴註胞二燐膽堿、能量等對癥治療,觀察組在此治療基礎上頭針及體針電針刺激20 min,併取"四神通、百會、足三裏"穴位註射單唾液痠四己糖神經節苷脂鈉.動態觀察治療前、7天、14天、21天腦電圖( EEG )病理性棘波振幅、跼部腦血流量( rCBF );測定血漿( CK-BB );採用新生兒20 項神經行為評分辦法( NBNA)評分併統計總有效率.結果:觀察組于第7天、14天、21天 CK-BB及EEG明顯降低、NBNA及rCBF顯著提高(F=33.579,P<0.05),總有效率達97.59%,與治療組比較P<0.05,差異均有統計學意義.結論:通過對缺血缺氧性腦病新生兒頭針、體針電針刺激可疏通經絡、激髮患兒經氣,鬆弛新生兒跼部腦缺血區血管平滑肌以改善腦缺血區微循環而達到增加腦血流量的目的,穴位註射單唾液痠四己糖神經節苷脂鈉可營養腦組織及脩複受損神經纖維而促進腦功能的恢複.
목적:연구전침연합혈위주사단타액산사기당신경절감지납치료신생인결혈결양성뇌병적림상료효급궤제,위차류질병제공신적종합치료방안.방법:선취2014 년3월~2015 년3 월본원수치적166례결혈결양성뇌병신생환인,안출생선후순서수궤분치료조、관찰조,치료조매일흡양급정맥적주포이린담감、능량등대증치료,관찰조재차치료기출상두침급체침전침자격20 min,병취"사신통、백회、족삼리"혈위주사단타액산사기당신경절감지납.동태관찰치료전、7천、14천、21천뇌전도( EEG )병이성극파진폭、국부뇌혈류량( rCBF );측정혈장( CK-BB );채용신생인20 항신경행위평분판법( NBNA)평분병통계총유효솔.결과:관찰조우제7천、14천、21천 CK-BB급EEG명현강저、NBNA급rCBF현저제고(F=33.579,P<0.05),총유효솔체97.59%,여치료조비교P<0.05,차이균유통계학의의.결론:통과대결혈결양성뇌병신생인두침、체침전침자격가소통경락、격발환인경기,송이신생인국부뇌결혈구혈관평활기이개선뇌결혈구미순배이체도증가뇌혈류량적목적,혈위주사단타액산사기당신경절감지납가영양뇌조직급수복수손신경섬유이촉진뇌공능적회복.
Objective:To study the effect of electroacupuncture combined with acupoint injection single sialic acid four hexose ganglioside sodium in the treatment of neonatal hypoxic ischemic encephalopathy,and to pro-vide a new scheme of comprehensive treatment.Methods:From March 2014 to March 2015 in our hospital 166 cases of neonatal hypoxic ischemic encephalopathy in children by birth order were randomly divided into a treat -ment group and an observation group.The treatment group was given oxygen inhalation and intravenous infusion of cytoplasmic two choline,energy and other symptomatic treatment,and the treatment group was given the treat-ment on the basis of scalp acupuncture and body acupuncture for 20 min with Sishentong,Baihui and Zusanli acupoint injection of monosialo four hexose ganglioside sodium;before treatment and after 7 d,14 d,21 d dy-namically observe the electroencephalogram,pathological EEG spike wave amplitude,regional cerebral blood flow(RCBF);determine the CreatinekinaseBB (CK-BB);adopt the 20 item neonatal behavioral neurological assessment ( NBNA) score and statistical measures of the total efficiency.Results:In the observation group at 7 d,14 d,21 d,CK-BB and EEG were decreased significantly (F=33.579,P<0.05).NBNA and RCBF were significantly improved and the total effective rate was 97.59%.The difference was statistically significant between the observation group and the treatment group (P<0.05).Conclusion:Hypoxic ischemic encephalopa-thy in neonatal scalp acupuncture,body acupuncture and electroacupuncture stimulation can dredge the meridi-ans,inspire children to Qi,relax the neonatal cerebral ischemic vascular and smooth muscle,which can im-prove microcirculation in the area of cerebral ischemia and increase blood flow of the brain.Acupoint injection single sialic acid four hexose sodium can nurture the brain and repair damaged nerve fibers and promote the re -covery of brain function.
