CAJ | 학술논문

目的：探讨脑卒中抑郁与神经功能缺损的相关性。方法选择2013年6月至2014年12月武汉市普仁医院收治的急性脑卒中患者120例为研究对象，根据抑郁自评量表（ SDS）进行初步诊断，再通过汉密尔顿抑郁量表（ HAMD ）进行测评，比较入院后第2日、第1周、第2周、第3周HAMD和斯堪的纳维亚神经功能缺损评分量表（ SSS）情况。结果120例患者中脑卒中患者中抑郁49例，发病率为40.8％，轻度抑郁患者12例（10.0％），中度抑郁患者21例（17.5％），重度抑郁患者16例（13.3％）；治疗后1、2、3周轻度抑郁、中度抑郁与重度抑郁患者的 HAMD 评分均呈上升趋势（P＜0.05）；单纯脑卒中组、轻度抑郁组治疗后1、2、3周SSS评分均呈上升趋势，中度抑郁组与重度抑郁组SSS评分呈下降趋势（P＜0.05）。中度抑郁组与重度抑郁组患者的 HAMD 评分与 SSS 评分呈正相关（ r＝5.102，P＜0.05）。结论急性脑卒中患者存在较高的抑郁发病率，抑郁状态加深与神经系统的缺损相关，尽早进行抑郁管理可以改善患者神经功能缺损情况。
목적：탐토뇌졸중억욱여신경공능결손적상관성。방법선택2013년6월지2014년12월무한시보인의원수치적급성뇌졸중환자120례위연구대상，근거억욱자평량표（ SDS）진행초보진단，재통과한밀이돈억욱량표（ HAMD ）진행측평，비교입원후제2일、제1주、제2주、제3주HAMD화사감적납유아신경공능결손평분량표（ SSS）정황。결과120례환자중뇌졸중환자중억욱49례，발병솔위40.8％，경도억욱환자12례（10.0％），중도억욱환자21례（17.5％），중도억욱환자16례（13.3％）；치료후1、2、3주경도억욱、중도억욱여중도억욱환자적 HAMD 평분균정상승추세（P＜0.05）；단순뇌졸중조、경도억욱조치료후1、2、3주SSS평분균정상승추세，중도억욱조여중도억욱조SSS평분정하강추세（P＜0.05）。중도억욱조여중도억욱조환자적 HAMD 평분여 SSS 평분정정상관（ r＝5.102，P＜0.05）。결론급성뇌졸중환자존재교고적억욱발병솔，억욱상태가심여신경계통적결손상관，진조진행억욱관리가이개선환자신경공능결손정황。
Objective To study the correlation between stroke depression and nerve function defect . Methods A total of 120 acute stroke patients admitted to Wuhan Puren Hospital during Jun .2013 and Dec. 2014 were included in the study,according to self-rating depression scale(SDS) the preliminary diagnosis was done,then the Hamilton depression scale ( HAMD) and the score of neural function defect scale ( Scan-dinavia SSS) were compared between the second day after admission and first week ,second week,third week after admission were compared.Results Among the 120 cases,49 patients had post-stroke depression,the incidence rate was 40.8%,12 cases with mild depression (10.0%),21 cases with moderate depression (17.5%),16 cases with severe depression(13.3%).1,2,3 weeks after treatment,mild depression,moder-ate depression and severe depression HAMD score showed an upward trend (P<0.05); after 1,2,3 weeks the simple stroke group,mild depression group treatment SSS rates showed an upward trend ,while the HAMD score and SSS score in the moderate depression group and severe depression group decreased ( P<0.05 ) . The HAMD score and SSS score in the moderate depression group and severe depression group was positive correlated(r =5.102,P <0.05).Conclusion The patients with acute stroke have higher incidence of depression,which is associated with the presence of defects of the nervous system and the depression state deepening,depression management as early as possible can improve the nerve function defect situation of the patients.