现代中西医结合杂志
現代中西醫結閤雜誌
현대중서의결합잡지
Modern Journal of Integrated Traditional Chinese and Western Medicine
2015年
34期
3775-3777
,共3页
贾琳%武蕾%郭勇英%刘伟花
賈琳%武蕾%郭勇英%劉偉花
가림%무뢰%곽용영%류위화
补肾通络方%支气管哮喘%缓解期%嗜酸性粒细胞阳离子蛋白
補腎通絡方%支氣管哮喘%緩解期%嗜痠性粒細胞暘離子蛋白
보신통락방%지기관효천%완해기%기산성립세포양리자단백
reinforcing kidney and smooth collaterals%bronchial asthma%remission stage%ECP
目的：观察从补肾、通络立法所拟方剂补肾通络方治疗支气管哮喘缓解期的临床效果。方法将60例支气管哮喘缓解期患者随机分为2组，对照组予沙美特罗／丙酸氟替卡松（50μg／250μg）早晚各1吸，治疗组在对照组治疗基础上予补肾通络方口服1剂／d，2组疗程均为3个月。观察治疗前及治疗后1年内2组哮喘急性发作次数，治疗前、治疗结束后及治疗结束6个月后2组哮喘控制测试表（ ACT ）的得分情况，测定2组用力肺活量（FVC）、第1秒用力呼气容积（FEV1）、最大呼气峰流速（PEF）的变化及血清嗜酸性粒细胞阳离子蛋白（ ECP）水平。结果治疗组治疗后1年内哮喘急性发作次数明显少于对照组（ P＜0．05），治疗结束后及治疗结束6个月后ACT得分均明显高于对照组（P均＜0．05），治疗后FVC、FEV1、PEF均明显高于对照组（P均＜0．05），血清ECP水平明显低于对照组（P＜0．05）。结论补肾通络方可有效减少哮喘患者急性发作次数，改善肺功能及气道炎症，值得推广应用。
目的：觀察從補腎、通絡立法所擬方劑補腎通絡方治療支氣管哮喘緩解期的臨床效果。方法將60例支氣管哮喘緩解期患者隨機分為2組，對照組予沙美特囉／丙痠氟替卡鬆（50μg／250μg）早晚各1吸，治療組在對照組治療基礎上予補腎通絡方口服1劑／d，2組療程均為3箇月。觀察治療前及治療後1年內2組哮喘急性髮作次數，治療前、治療結束後及治療結束6箇月後2組哮喘控製測試錶（ ACT ）的得分情況，測定2組用力肺活量（FVC）、第1秒用力呼氣容積（FEV1）、最大呼氣峰流速（PEF）的變化及血清嗜痠性粒細胞暘離子蛋白（ ECP）水平。結果治療組治療後1年內哮喘急性髮作次數明顯少于對照組（ P＜0．05），治療結束後及治療結束6箇月後ACT得分均明顯高于對照組（P均＜0．05），治療後FVC、FEV1、PEF均明顯高于對照組（P均＜0．05），血清ECP水平明顯低于對照組（P＜0．05）。結論補腎通絡方可有效減少哮喘患者急性髮作次數，改善肺功能及氣道炎癥，值得推廣應用。
목적：관찰종보신、통락입법소의방제보신통락방치료지기관효천완해기적림상효과。방법장60례지기관효천완해기환자수궤분위2조，대조조여사미특라／병산불체잡송（50μg／250μg）조만각1흡，치료조재대조조치료기출상여보신통락방구복1제／d，2조료정균위3개월。관찰치료전급치료후1년내2조효천급성발작차수，치료전、치료결속후급치료결속6개월후2조효천공제측시표（ ACT ）적득분정황，측정2조용력폐활량（FVC）、제1초용력호기용적（FEV1）、최대호기봉류속（PEF）적변화급혈청기산성립세포양리자단백（ ECP）수평。결과치료조치료후1년내효천급성발작차수명현소우대조조（ P＜0．05），치료결속후급치료결속6개월후ACT득분균명현고우대조조（P균＜0．05），치료후FVC、FEV1、PEF균명현고우대조조（P균＜0．05），혈청ECP수평명현저우대조조（P＜0．05）。결론보신통락방가유효감소효천환자급성발작차수，개선폐공능급기도염증，치득추엄응용。
Objective It is to observe the clinical effects of reinforcing kidney and smooth collaterals decoction on remis -sion stage of bronchial asthma .Methods 60 patients with bronchial asthma were randomly divided into 2 groups: the control group and treatment group .Patients in control group were received the Salmeterol and fluticasone propionate powder (50/250) twice a day, while patients in treatment group were received reinforcing kidney and smooth collaterals decoction ,both the treatment course were 3 months.Before and after treatment , the number of acute bout of asthma in one year ,ACT values of two groups were observed;the lung function and the levels of ECP in serum were measured respectively .Results Compared with control group, the number of acute bout of asthma in one year in treatment group were lower (P<0.05).ACT value, the lev-els of FVC, FEV1 and PEF in treatment group were higher (P<0.05),while the levels of ECP in serum were lower (P<0. 05 ) after treatment .Conclusion Reinforcing kidney and smooth collaterals decoction could reduce the number of acute bout of asthma,it could relieve the lung function and airway inflammation .This method was worth generalizing and applying .
