CAJ | 학술논문

目的：比较气管内插管下全凭静脉麻醉与吸入七氟醚静吸复合麻醉在腹腔镜胆囊切除术中的麻醉应用效果及经济学分析。方法择期行腹腔镜胆囊切除术患者40例，随机分为两组，均使用丙泊酚、舒芬太尼、顺式阿曲库铵行麻醉诱导，Ⅰ组靶控输注（ TCI ）丙泊酚维持，Ⅱ组吸入七氟醚维持，术中按需追加舒芬太尼、顺式阿曲库铵维持镇痛与肌松。术中不同时点观察记录麻醉效果，术毕记录麻醉药品消耗量，比较分析两组的麻醉效果及经济学分析。结果两组患者麻醉时间、术中麻醉监控各指数均无统计学差异，麻醉术后并发症Ⅰ组显著低于Ⅱ组，而麻醉用药费用Ⅰ组显著高于Ⅱ组（502．4±81．2 vs．441．0±99．3元，P＜0．05）。结论腹腔镜胆囊切除术中，全凭静脉TCI丙泊酚维持麻醉安全可控，有较少的麻醉并发症，但比吸入七氟醚静吸复合麻醉的麻醉用药费用更高。
목적：비교기관내삽관하전빙정맥마취여흡입칠불미정흡복합마취재복강경담낭절제술중적마취응용효과급경제학분석。방법택기행복강경담낭절제술환자40례，수궤분위량조，균사용병박분、서분태니、순식아곡고안행마취유도，Ⅰ조파공수주（ TCI ）병박분유지，Ⅱ조흡입칠불미유지，술중안수추가서분태니、순식아곡고안유지진통여기송。술중불동시점관찰기록마취효과，술필기록마취약품소모량，비교분석량조적마취효과급경제학분석。결과량조환자마취시간、술중마취감공각지수균무통계학차이，마취술후병발증Ⅰ조현저저우Ⅱ조，이마취용약비용Ⅰ조현저고우Ⅱ조（502．4±81．2 vs．441．0±99．3원，P＜0．05）。결론복강경담낭절제술중，전빙정맥TCI병박분유지마취안전가공，유교소적마취병발증，단비흡입칠불미정흡복합마취적마취용약비용경고。
Objective To compare the anesthesia drug costs in anesthesia endotracheal intubation total intravenous with sevoflurane inhalation anesthesia in laparoscopic cholecystectomy surgery .Methods Forty patients underwent laparoscopic cholecystectomy were randomly divided into two groups equally , with n=20 in each group.All patients were induced by propofol , sufentanil and cis-atracurium, group I received target controlled infusion ( TCI) of propofol to maintain , group II received sevoflurane to maintain .sufentanil and cis-atracurium was provided to maintain analgesia and muscle relaxation during the operation .Sedation depth was monitored by the anesthesia depth index (Narcotrend index, NI), and the NI was set in D grade.Anesthetic consumption and calculate drug costs was recorded and compared based on various narcotics unit .Results There was no significant difference in the patients demographic , anesthesia time and operation time .The drug cost was (502.4 ±81.2 Yuan, 5.9 ±1.0 Yuan/min) and (441.0 ±99.3 Yuan, 5.4 ±0.8 Yuan/min) in group I and group II, respectively.Group I was higher than group II ( P <0.05).Conclusions TCI propofol-based anesthesia was associated with higher costs than inhaled anesthetics sevoflurane .