黔南民族医专学报
黔南民族醫專學報
검남민족의전학보
Journal of Qiannan Medical College for Nationalities
2015年
3期
180-183
,共4页
鸡冠花白果止带汤%细菌性阴道病%免疫球蛋白%T 细胞亚群
鷄冠花白果止帶湯%細菌性陰道病%免疫毬蛋白%T 細胞亞群
계관화백과지대탕%세균성음도병%면역구단백%T 세포아군
Ji Guan Hua Bai Guo Zhi Dai Tang (JGHBGZDT)%bacterial vaginosis (BV)%immuno-globulin%T cell subgroup
目的：研究鸡冠花白果止带汤对细菌性阴道病（脾虚湿热型）患者免疫功能的影响。方法：将60例细菌性阴道病患者随机分为治疗组和对照组。治疗组采用自拟方剂“鸡冠花白果止带汤”治疗；对照组采用甲硝唑口服、双唑泰栓局部给药。观察患者临床疗效并检测治疗前后血清免疫球蛋白（IgG、IgA、IgM）水平，以及外周血中 T 细胞亚群水平的变化，分析该方对细菌性阴道病（脾虚湿热型）患者的影响，初步探讨鸡冠花白果止带汤治疗细菌性阴道病的免疫调节机制。结果：1.总有效率治疗组为90％；对照组为76.67％，差异有显著性意义（P ＜0.05）；2.治疗前后免疫球蛋白水平和 CD3＋、CD4＋、CD8＋、CD4＋／CD8＋比较，差异有显著性意义（P ＜0.05）。结论：鸡冠花白果止带汤治疗细菌性阴道病的临床疗效优于对照组，并能提高患者的免疫功能。
目的：研究鷄冠花白果止帶湯對細菌性陰道病（脾虛濕熱型）患者免疫功能的影響。方法：將60例細菌性陰道病患者隨機分為治療組和對照組。治療組採用自擬方劑“鷄冠花白果止帶湯”治療；對照組採用甲硝唑口服、雙唑泰栓跼部給藥。觀察患者臨床療效併檢測治療前後血清免疫毬蛋白（IgG、IgA、IgM）水平，以及外週血中 T 細胞亞群水平的變化，分析該方對細菌性陰道病（脾虛濕熱型）患者的影響，初步探討鷄冠花白果止帶湯治療細菌性陰道病的免疫調節機製。結果：1.總有效率治療組為90％；對照組為76.67％，差異有顯著性意義（P ＜0.05）；2.治療前後免疫毬蛋白水平和 CD3＋、CD4＋、CD8＋、CD4＋／CD8＋比較，差異有顯著性意義（P ＜0.05）。結論：鷄冠花白果止帶湯治療細菌性陰道病的臨床療效優于對照組，併能提高患者的免疫功能。
목적：연구계관화백과지대탕대세균성음도병（비허습열형）환자면역공능적영향。방법：장60례세균성음도병환자수궤분위치료조화대조조。치료조채용자의방제“계관화백과지대탕”치료；대조조채용갑초서구복、쌍서태전국부급약。관찰환자림상료효병검측치료전후혈청면역구단백（IgG、IgA、IgM）수평，이급외주혈중 T 세포아군수평적변화，분석해방대세균성음도병（비허습열형）환자적영향，초보탐토계관화백과지대탕치료세균성음도병적면역조절궤제。결과：1.총유효솔치료조위90％；대조조위76.67％，차이유현저성의의（P ＜0.05）；2.치료전후면역구단백수평화 CD3＋、CD4＋、CD8＋、CD4＋／CD8＋비교，차이유현저성의의（P ＜0.05）。결론：계관화백과지대탕치료세균성음도병적림상료효우우대조조，병능제고환자적면역공능。
Objective:To study the effect of Ji Guan Hua Bai Guo Zhi Dai Tang (JGHBGZDT)on the immune function of patients with bacterial vaginal disease.Methods:A total of 90 patients diagnosed of bac-terial vaginal disease were randomly divided into treatment group,control group 1,and control group 2.The treatment group was treated with JGHBGZDT,the control group 1 was treated with Wan Dai Tang,and the control group 2 was treated with metronidazole and Metronidazole.The clinical curative effect of treatment and testing level of immunoglobulin and T cell subgroup in peripheral blood was observed before and after the treat-ment.The effects of JGHBGZDT on bacterial vaginal disease were analyzed..Results:The total effective rate in treatment group was 90%,which was 73.33% and 76.67% in control group 1 and 2.The level of IgG, IgA,IgM,CD3 +,CD4 +and CD4 +/CD8 + were significantly higher after treatment than between before treatment and the control group (all P <0.05).Conclusion:JGHBGZDT has better effect in treatment of bacterial vaginal disease clinical curative than the control group and can improve the patient's immune func-tion.
