CAJ | 학술논문

目的：对89Sr治疗骨转移癌患者的临床效果进行评价。方法研究对象为我科收治的60例骨转移癌患者,均行89Sr治疗,总治疗次数为76次,每例患者每次89Sr计量为4mci。分别于治疗前和治疗后3个月对患者实施全身骨显像检查,记录患者骨痛消失、开始缓解、缓解持续和复发时间。结果全身骨显像检查显示,患者病灶数目明显减少、病灶范围缩小,病灶放射性计数减少,临床治疗总有效率为87%,药物不良反应发生率为35%,患者主观骨痛反应玉级率为53.3%,Ⅱ级率为33.3%,与治疗前比较差异具有统计学意义(<0.05)。结论89Sr治疗骨转移癌,疗效确切,安全性高。
목적：대89Sr치료골전이암환자적림상효과진행평개。방법연구대상위아과수치적60례골전이암환자,균행89Sr치료,총치료차수위76차,매례환자매차89Sr계량위4mci。분별우치료전화치료후3개월대환자실시전신골현상검사,기록환자골통소실、개시완해、완해지속화복발시간。결과전신골현상검사현시,환자병조수목명현감소、병조범위축소,병조방사성계수감소,림상치료총유효솔위87%,약물불량반응발생솔위35%,환자주관골통반응옥급솔위53.3%,Ⅱ급솔위33.3%,여치료전비교차이구유통계학의의(<0.05)。결론89Sr치료골전이암,료효학절,안전성고。
Objective To evaluate the clinical ef ect of 89Sr in the treatment of patients with bone metastases. Methods Selected 60 cases of patients with bone metastasis in our department. The total number of patients treated with 89Sr was 76 times, and the number of patients with 89Sr was 4mci. Before and after 3 months in patients with implementation of whole body bone imaging, recorded the time of bone pain disappeared, began to ease, sustained remission and relapse. Results As whole body bone imaging examination showed, which significantly reduced the number of patients with lesions, nar ow the scope of lesions and lesions radioactive counts, the clinical treatment of total ef iciency was 87%, and the adverse drug reactions occur ed rate was 35%. The patients subjective pain reaction I grade rate was 53.3%, grade II rate was 33.3%, which has statistical significance as compared with that before treatment ( < 0.05). Conclusion 89Sr in the treatment of bone metastasis cancer has good curative ef ect and is safe.