CAJ | 학술논문

目的：：观察糖尿病肾病患者经中西医结合治疗好转后,其糖尿病视网膜病变是否也会随之好转。方法：选取我院2010年1月~2013年12月期间,糖尿病肾病(DN)3~4期合并糖尿病视网膜病变(DR)Ⅰ~Ⅲ期的患者78例,给予黄芪颗粒15g,1d2次,以及氯沙坦片50~100mg/次,1d1次治疗。观察治疗前后空腹血糖(FBP)、糖化血红蛋白(HbA1C),尿白蛋白肌酐比值(UACR),视力和眼底荧光造影结果的变化。同时观察 DN 不同转归患者 DR 的变化情况。结果：经过治疗,患者空腹血糖(FBP)、糖化血红蛋白(HbA1C),尿白蛋白肌酐比值(UACR)水平均较前好转；治疗前后视力变化无明显统计学差异；DN 治疗有效组中DR治疗的有效率,相对DN治疗无效组为多,有统计学差异。结论：在糖尿病肾病经中西医结合治疗有效后,大部分患者的糖尿病视网膜病变也得到了好转。
목적：：관찰당뇨병신병환자경중서의결합치료호전후,기당뇨병시망막병변시부야회수지호전。방법：선취아원2010년1월~2013년12월기간,당뇨병신병(DN)3~4기합병당뇨병시망막병변(DR)Ⅰ~Ⅲ기적환자78례,급여황기과립15g,1d2차,이급록사탄편50~100mg/차,1d1차치료。관찰치료전후공복혈당(FBP)、당화혈홍단백(HbA1C),뇨백단백기항비치(UACR),시력화안저형광조영결과적변화。동시관찰 DN 불동전귀환자 DR 적변화정황。결과：경과치료,환자공복혈당(FBP)、당화혈홍단백(HbA1C),뇨백단백기항비치(UACR)수평균교전호전；치료전후시력변화무명현통계학차이；DN 치료유효조중DR치료적유효솔,상대DN치료무효조위다,유통계학차이。결론：재당뇨병신병경중서의결합치료유효후,대부분환자적당뇨병시망막병변야득도료호전。
Obj ective:To observe whether diabetic nephropathy(DN)patients treated by integrated traditional Chinese and western medicine,their diabetic retinopathy(DR)was also improved.Methods :From January 2010 to De-cember 2013,78 patients with diabetic nephropathy (DN)3~4 stage and diabetic retinopathy (DR)I~III stage were se-lected.They were treated with Astragalus granule 15g/times,bid,and losartan tablets 50~100mg/times,qd.The changes of FBP,HbA1C,UACR,vision and fundus fluorescein angiography were observed before and after treatment. The changes of DR in different DN patients were also observed.Results:After treatment,FBP,HbA1C and UACR of patients were significantly improved than before.There was no significant difference in visual acuity before and after treat-ment.DR treatment efficiency in the DN effective group was better than DR treatment efficiency in the DN ineffective group,and there were statistical differences between them.Conclusions:In ND patients treated effectively by integrated traditional Chinese and western medicine,the majority of patients with DR has also been improved.