CAJ | 학술논문

目的：探讨圆锥角膜和近视人群波前像差及屈光参数的差异性,为临床实践提供一定的依据方法随机收集2012年5月~2015年5月,在我院眼科门诊就诊的16例(32眼)的双眼原发性圆锥角膜病例和16例(32眼)双眼近视的病例,圆锥角膜患者为A组,近视患者为B组。检查者测量病例受试者双眼像差,双眼屈光不正度数；眼轴长AL,前房深度ACD,角膜曲率。运用SPSS17.0统计分析软件分别进行圆锥角膜和近视人群高阶像差对等效球镜SE、眼轴AL、角膜曲率及前房深度ACD的相关分析,并比较二者的差异性。结果首先F检验显示两组的数据方差齐性(>0.05),运用独立样本T检验结果显示：圆锥角膜和近视的患者相比较,其一些高阶波前像差值(球差、彗差、四叶草)、角膜曲率及前房深度都会增大。Pearson双变量相关分析显示：在圆锥角膜病例中,年龄和眼轴长、眼轴长和前房深度、角膜曲率和年龄、角膜曲率和前房深度均显示显著性正相关,年龄和等效球镜、等效球镜和眼轴长、等效球镜和前房深度显著性负相关；等效球镜和球差、前方深度和慧差、前方深度和球差、角膜曲率和球差、角膜曲率和慧差、角膜曲率和四叶草均显示显著性正相关,年龄和慧差呈显著性负相关。而在近视人群中,年龄和眼轴长、眼轴长和前房深度显著性正相关,年龄和等效球镜、等效球镜和眼轴长、等效球镜和前房深度显著性负相关；等效球镜和球差、前房深度和彗差、前房深度和球差显著性正相关。结论在圆锥角膜及近视病例研究都显示：等效球镜和年龄,眼轴长和前房深度,等效球镜以及前房深度和高阶波前像差(球差和慧差)有密切相关性；圆锥角膜病例中,年龄、角膜曲率对像差的影响显著。研究结果亦显示,随着等效球镜向近视方向发展,球差值会增大；慧差和眼轴长及前房深度均呈正相关。目的：探討圓錐角膜和近視人群波前像差及屈光參數的差異性,為臨床實踐提供一定的依據方法隨機收集2012年5月~2015年5月,在我院眼科門診就診的16例(32眼)的雙眼原髮性圓錐角膜病例和16例(32眼)雙眼近視的病例,圓錐角膜患者為A組,近視患者為B組。檢查者測量病例受試者雙眼像差,雙眼屈光不正度數；眼軸長AL,前房深度ACD,角膜麯率。運用SPSS17.0統計分析軟件分彆進行圓錐角膜和近視人群高階像差對等效毬鏡SE、眼軸AL、角膜麯率及前房深度ACD的相關分析,併比較二者的差異性。結果首先F檢驗顯示兩組的數據方差齊性(>0.05),運用獨立樣本T檢驗結果顯示：圓錐角膜和近視的患者相比較,其一些高階波前像差值(毬差、彗差、四葉草)、角膜麯率及前房深度都會增大。Pearson雙變量相關分析顯示：在圓錐角膜病例中,年齡和眼軸長、眼軸長和前房深度、角膜麯率和年齡、角膜麯率和前房深度均顯示顯著性正相關,年齡和等效毬鏡、等效毬鏡和眼軸長、等效毬鏡和前房深度顯著性負相關；等效毬鏡和毬差、前方深度和慧差、前方深度和毬差、角膜麯率和毬差、角膜麯率和慧差、角膜麯率和四葉草均顯示顯著性正相關,年齡和慧差呈顯著性負相關。而在近視人群中,年齡和眼軸長、眼軸長和前房深度顯著性正相關,年齡和等效毬鏡、等效毬鏡和眼軸長、等效毬鏡和前房深度顯著性負相關；等效毬鏡和毬差、前房深度和彗差、前房深度和毬差顯著性正相關。結論在圓錐角膜及近視病例研究都顯示：等效毬鏡和年齡,眼軸長和前房深度,等效毬鏡以及前房深度和高階波前像差(毬差和慧差)有密切相關性；圓錐角膜病例中,年齡、角膜麯率對像差的影響顯著。研究結果亦顯示,隨著等效毬鏡嚮近視方嚮髮展,毬差值會增大；慧差和眼軸長及前房深度均呈正相關。
목적：탐토원추각막화근시인군파전상차급굴광삼수적차이성,위림상실천제공일정적의거방법수궤수집2012년5월~2015년5월,재아원안과문진취진적16례(32안)적쌍안원발성원추각막병례화16례(32안)쌍안근시적병례,원추각막환자위A조,근시환자위B조。검사자측량병례수시자쌍안상차,쌍안굴광불정도수；안축장AL,전방심도ACD,각막곡솔。운용SPSS17.0통계분석연건분별진행원추각막화근시인군고계상차대등효구경SE、안축AL、각막곡솔급전방심도ACD적상관분석,병비교이자적차이성。결과수선F검험현시량조적수거방차제성(>0.05),운용독립양본T검험결과현시：원추각막화근시적환자상비교,기일사고계파전상차치(구차、혜차、사협초)、각막곡솔급전방심도도회증대。Pearson쌍변량상관분석현시：재원추각막병례중,년령화안축장、안축장화전방심도、각막곡솔화년령、각막곡솔화전방심도균현시현저성정상관,년령화등효구경、등효구경화안축장、등효구경화전방심도현저성부상관；등효구경화구차、전방심도화혜차、전방심도화구차、각막곡솔화구차、각막곡솔화혜차、각막곡솔화사협초균현시현저성정상관,년령화혜차정현저성부상관。이재근시인군중,년령화안축장、안축장화전방심도현저성정상관,년령화등효구경、등효구경화안축장、등효구경화전방심도현저성부상관；등효구경화구차、전방심도화혜차、전방심도화구차현저성정상관。결론재원추각막급근시병례연구도현시：등효구경화년령,안축장화전방심도,등효구경이급전방심도화고계파전상차(구차화혜차)유밀절상관성；원추각막병례중,년령、각막곡솔대상차적영향현저。연구결과역현시,수착등효구경향근시방향발전,구차치회증대；혜차화안축장급전방심도균정정상관。
Objective To explore the keratoconus and myopic crowd of the dif erence of wavefront aber ation and refractive parameters provide a basis for clinical practice.Methods 16 patients af ected by keratoconus (32 eyes)and 16 patients with myopes (32 eyes)were recruited from outpatient clinic randomly.Group A are keratoconus,and Group B are myopes.wavefront aberrations,degrees of refraction was measured using auto refractor,axial length (AL)and anterior chamber depth (ACD)and corneal curvature were measured by the same doctor.SPSS software package 17.0 were applied to perform the data analysis.Results Data showed that some higher order aber ations (sphere-aber ation, coma-aber ation and quadrafoil)anterior chamber depth and corneal curvature wil increase in patients with keratoconus compared to myopes (the results were analyzed with the Matching T test)Pearson test in patients with keratoconus (Group A)statistics showed that Age and AL,AL and ACD, corneal curvature and Age,corneal curvature and ACD had positive cor elations,Age and SE,SE and AL,SE and ACD had negative cor elations;SE and sphere-aber ation,ACD and coma-aberration, ACD and sphere-aberration,corneal curvature and sphere-aber ation,corneal curvature and coma-aber ation,corneal curvature and quadrafoil had positive cor elations,Age and coma-aber ation had negative cor elations;Pearson test in patients with myopes (Group B)Age and AL,AL and ACD had positive correlations,Age and SE,SE and AL,SE and ACD had negative cor elations;SE and sphere-aber ation,ACD and coma-aber ation,ACD and sphere-aber ation had positive cor elations .Conclusion Both keratoconus and myopes,SE and Age,AL,SE,higher order aber ations (sphere-aberration, coma-aber ation)and ACD were wel cor elated.In patients with keratoconus,Age and corneal curvature had significant influence in ocular aber ations.Sphere-aber ation was increased as SE developed to myopia.Coma-aber ation,AL and ACD have-positive-cor elations.